변직성 경부경화증은 정제제로 치료할 수 있나요? 근거에 따른 증거는 무엇인가?

최종 업데이트: 2026년 8월 27일

• WordPress
• LinkedIn
• 메일

Men who have been told they have a varicocele reasonably ask whether there is a tablet for it, particularly when the problem is a dull ache rather than a fertility question. The short answer is worth stating before anything else.

No medication corrects a varicocele. The dilated veins remain dilated. What is discussed on this page is whether a drug can ease the 증상 in a man who does not want an operation — a narrower question, and one where the evidence is thinner than it is usually presented.

For what a varicocele is, when it needs treating and when it does not, start with the varicocele overview.

• 태국 방콕 병원 비뇨의학 센터 온라인 예약 02-310-3009 bhquro@bdms.co.th
• Samitivej Sriracha Hospital 촌부리 088-022-1445

The reasoning behind trying a tablet

The testicle works best a couple of degrees below core body temperature. A varicocele lets blood at full body temperature pool around it, and that — together with oxidative stress and the pressure of the pooled blood — is how it interferes with sperm production and produces the heavy, aching sensation men describe at the end of a long day standing.

Since the problem is essentially a plumbing one, the drugs that have been tried are venoactive agents — the same class vascular specialists use for varicose veins in the leg. The best studied is micronised purified flavonoid fraction, usually shortened to MPFF, which improves the tone of vein walls and reduces pressure within them.

An earlier version of this article described MPFF as the only scientifically approved oral medication for varicocele. That overstates its status and has been corrected — it is licensed for chronic venous disease of the legs, and its use for varicocele is off-label and supported by small studies rather than by regulatory approval for this purpose.

Reading the trial figures properly

이 study usually cited reported that after six months, 87.5% of men were completely free of testicular discomfort and the remaining 12.5% were significantly improved. Those numbers are quoted widely, including in the earlier version of this article, and they deserve a moment’s attention.

They add up to 100%. Every single man improved and not one failed to. No treatment in medicine performs like that, and a result of that shape tells you what kind of study it was: a small one, without a comparison group.

That matters because varicocele pain is exactly the sort of symptom that improves on its own. It fluctuates, it responds to attention and expectation, and men enrolling in a study for it are usually at their worst when they start. Without a group taking a dummy tablet, there is no way to separate the drug from all of that. The honest reading is that MPFF may help varicocele-related pain, on weak evidence — not that it relieves it in everybody.

And on fertility

The same study reported improved sperm motility, with no improvement in semen volume, concentration or morphology. One parameter moving in a small uncontrolled study is not a fertility treatment, and MPFF should not be taken in place of proper assessment by a couple who are trying to conceive. Where a palpable varicocele sits alongside an abnormal semen analysis, the discussion is about surgery or embolisation — see the overview, 그리고 정액 검사 결과지 읽는 법 before drawing conclusions from one.

What to try first, if the problem is the ache

These are simple, free or nearly so, and often enough on their own — and the earlier version of this article went straight to medication without mentioning them.

• Supportive underwear rather than loose, particularly on days spent standing.
• Lying down when it aches. A varicocele drains when you are horizontal, which is why the discomfort eases — and why a swelling that does 않는다 settle when you lie flat needs looking into rather than tolerating.
• Simple painkillers for bad days, and breaking up long periods of standing where work allows.
• Confirming the varicocele is actually the cause. This is the step most often skipped. Scrotal ache has other explanations, and men with a varicocele found incidentally sometimes have their pain attributed to it and then treated for years without benefit.

Where those fail and the pain is genuinely attributable, a trial of a venoactive drug is a reasonable next step before considering surgery, provided you understand what it is and is not likely to do. If it has not helped after a few months, it is not going to.

Findings that need attention rather than a tablet

태국에서 응급 상황이 발생하면 다음 번호로 전화하십시오: 1669.

• A varicocele on the right side only, one that has appeared suddenly, or one that does not drain away when you lie down. These patterns can indicate something in the abdomen pressing on the vein and need imaging rather than treatment for symptoms.
• 갑작스러운 극심한 고환 통증 — 당일 응급 상황이며 정계정맥류가 아닙니다.
• 고환 자체 내부의 단단한 덩어리, as distinct from the soft veins above it.
• 한쪽 고환이 다른쪽보다 눈에 띄게 작아지는 것, 특히 청소년에게서 나타나는 경우.

자주 묻는 질문 (FAQ)

Can a varicocele be cured without surgery?

The varicocele itself cannot be corrected by any tablet — the dilated veins remain. What medication may do is ease the pain. An earlier version of this article answered this question with a plain yes, which conflated relieving a symptom with treating the condition.

Does MPFF really relieve pain in nearly everyone?

Those figures come from a small study with no comparison group, and they total 100% — every man improved and none failed to, which no treatment achieves. Varicocele pain fluctuates and improves on its own, so without a placebo group the drug cannot be separated from natural improvement. It may help; the evidence is weak.

Will tablets improve my fertility?

They should not be relied on for that. One study reported improved sperm motility with no change in volume, concentration or morphology, which is not a basis for treating infertility. A couple trying to conceive should be assessed properly rather than taking a venoactive drug and waiting.

What should I try first for the ache?

Supportive underwear, lying down when it aches, simple painkillers on bad days, and breaking up long periods of standing. Also worth confirming that the varicocele is genuinely the cause, since scrotal ache has other explanations and an incidentally found varicocele is often blamed for pain it is not causing.

How long should I give it?

A few months is a fair trial. If the pain has not eased by then, it is not going to, and continuing indefinitely is not the answer — that is the point to discuss surgery or embolisation.

진료 상담 예약 안내

Dr. Soarawee Weerasopone sees andrology and male fertility patients at Bangkok Hospital Headquarters 그리고 촌부리의 Samitivej Sriracha Hospital에서 진료하는 요일: 088-022-1445. Bring any semen analysis reports with their dates, and a list of anything you are already taking for the pain.

직접 내원하기 어려운 해외 환자분들을 포함한 환자분들을 위해 Bangkok Hospital 원격진료를 이용하실 수 있습니다. 비뇨기과 이메일로 미리 예약해 주세요: bhquro@bdms.co.th. Samitivej Sriracha는 대면 진료만 가능합니다. 비용에 관한 문의는 이 웹사이트가 아닌 병원에서 답변해 드립니다.

면책 조항: 이 콘텐츠는 Bangkok Hospital Headquarters의 비뇨의학과 전문의인 Dr. Soarawee Weerasopone이 작성하고 감수한 것으로, 교육 목적으로만 제공됩니다. 개인에 대한 의학적 조언, 진단 또는 처방이 아니며, 개인 메시지 채널이나 소셜 미디어를 통해서는 어떠한 조언, 진단 또는 처방도 제공되지 않습니다. Dr. Soarawee는 공개 소셜 미디어 계정을 운영하지 않으며, 그의 이름으로 개인 상담을 제안하는 모든 계정은 사기입니다. 태국에서 응급 상황이 발생하면 다음 번호로 전화하십시오: 1669.