Chronic Prostatitis Treatment Options

Q: What is the difference between bacterial and nonbacterial chronic prostatitis?

Bacterial chronic prostatitis (Category II) is confirmed bacterial infection treated with long-term antibiotics. Nonbacterial chronic prostatitis (Category III / CPPS) has no bacterial cause and accounts for most cases. Antibiotics are central to bacterial prostatitis; alpha blockers are the primary pharmacological option for CPPS.

Q: What antibiotics are used for chronic bacterial prostatitis and how long is treatment?

Ciprofloxacin (75% cure rate, up to 259 days), TMP-SMX (67% cure rate, up to 140 days), and Amoxicillin-clavulanate for 6 weeks in resistant cases. Adding alpha blockers (Terazosin or Alfuzosin) to antibiotics significantly improves cure rates and reduces recurrence.

Q: What is the treatment for nonbacterial chronic prostatitis?

Alpha blockers (Terazosin or Alfuzosin) are the most scientifically supported pharmacological treatment for CPPS, relaxing prostate and bladder neck smooth muscle to reduce voiding symptoms and pelvic pain. Treatment is individualized with the primary goal of improving quality of life.

បានធ្វើបច្ចុប្បន្នភាពចុងក្រោយ៖ ខែឧសភា 18, 2026

Soaravy Weerasopone, ឯកទេសប្រព័ន្ធទឹកនោម

ជ្ឈមណ្ឌលកណ្តាលនៃមន្ទីរពេទ្យបាងកក។

មន្ទីរពេទ្យ Samitivej Sriracha, Chonburi

ទំនាក់ទំនង LINE

Chronic prostatitis or chronic inflammation of the prostate gland is considered a difficult-to-treat issue in the urology office. This topic will give you a whole picture of chronic prostatitis treatment. This condition is divided into 2 categories by its natural history, with entirely different management spectrums. The following recommendation is based on scientific data referenced from US literature published in 2000.

មជ្ឈមណ្ឌលផ្នែកជម្ងឺប្រព័ន្ធទឹកនោមនៃមន្ទីរពេទ្យបាងកក ប្រទេសថៃ។ កក់លេខរៀងការណាត់ជួបតាម online 02-310-3009 bhquro@bdms.co.th
មន្ទីរពេទ្យ Samitivej Sriracha ខេត្តឈុនបូរី។ 088-022-1445

Most common etiology of chronic prostatitis is bacterial-caused.

ការណែនាំអំពីការព្យាបាលជំងឺរលាកក្រពេញប្រូស្តាតរ៉ាំរ៉ៃ

ការបង្ករអោយមានការលាកដោយពពួកបាតេរី
- ការប្រើថ្នាំផ្សះ
  - Ciprofloxacin – 75% cure rate with up to 259 days of treatment
  - Amoxicillin-clavulanate – 6-week alternative for suspected ciprofloxacin-resistant pathogen
  - Trimethoprim-sulfamethoxazole (TMP-SMX) – 67% cure rate with up to 140 days of treatment
- Alpha blockers (Terazosin or Alfuzosin) – when used in combination with antibiotics, clinical studies show significantly higher improvement rates and lower recurrence rates

Long-term oral antibiotic is recommended when bacterial-caused prostatitis is suspected.

Nonbacterial-caused prostatitis (Chronic Pelvic Pain Syndrome)
- Alpha blockers (Terazosin or Alfuzosin) – clinical studies show significantly higher improvement rates and lower recurrence rates

There is not a lot of high-level evidence-based treatment options in chronic prostatitis management. This condition requires proper individualized treatment designation based on the patient’s complaint and symptoms, because the main objective in chronic prostatitis treatment is to improve the patient’s quality of life.

“Improving on quality of life” is the main treatment objective in chronic prostatitis.

If you have any questions, please discuss with your trusted urologist, or you are welcome to contact me directly.

អ្នកអាចចូលមើលគេហទំព័រផ្លូវការរបស់ខ្ញុំ នៅទីនេះ.

Frequently Asked Questions About Chronic Prostatitis Treatment

What is the difference between bacterial and nonbacterial chronic prostatitis?

Bacterial chronic prostatitis (Category II) is caused by a confirmed bacterial infection of the prostate gland and is treated with long-term antibiotics. Nonbacterial chronic prostatitis (Category III, also called Chronic Pelvic Pain Syndrome or CPPS) has no identifiable bacterial cause and accounts for the majority of chronic prostatitis cases. The two types require different treatment strategies — antibiotics are central to bacterial prostatitis, while alpha blockers are the primary pharmacological option for CPPS.

What antibiotics are used for chronic bacterial prostatitis and how long is treatment?

The evidence-based antibiotic options are Ciprofloxacin (75% cure rate, up to 259 days of treatment), Trimethoprim-sulfamethoxazole (67% cure rate, up to 140 days), and Amoxicillin-clavulanate as a 6-week alternative for suspected Ciprofloxacin-resistant pathogens. Adding an alpha blocker (Terazosin or Alfuzosin) to antibiotics significantly improves cure rates and reduces recurrence compared to antibiotics alone.

What is the treatment for nonbacterial chronic prostatitis?

For nonbacterial chronic prostatitis (CPPS), alpha blockers such as Terazosin or Alfuzosin are the most scientifically supported pharmacological treatment. They relax the smooth muscle of the prostate and bladder neck, reducing voiding symptoms and pelvic pain. Because CPPS has many overlapping symptom domains, treatment is always individualized — the primary goal is improving quality of life rather than achieving a biochemical cure.

If you are experiencing chronic pelvic pain, urinary symptoms, or symptoms suggesting chronic prostatitis, Dr. Soarawee Weerasopone offers specialist consultations at Bangkok Hospital Headquarters. កក់ការពិគ្រោះយោបល់.

ការបដិសេធ៖ ខ្លឹមសារនេះត្រូវបានសរសេរ និងពិនិត្យដោយលោកវេជ្ជបណ្ឌិត Soarawee Weerasopone ដែលជាគ្រូពេទ្យឯកទេសខាងប្រព័ន្ធទឹកនោមដែលមានវិញ្ញាបនបត្រនៅទីស្នាក់ការកណ្តាលមន្ទីរពេទ្យបាងកក។ វាត្រូវបានបម្រុងទុកសម្រាប់គោលបំណងអប់រំតែប៉ុណ្ណោះ ហើយមិនមែនជាដំបូន្មានផ្នែកវេជ្ជសាស្ត្រទេ។ តែងតែពិគ្រោះជាមួយអ្នកជំនាញថែទាំសុខភាពដែលមានសមត្ថភាពមុនពេលចាប់ផ្តើមការព្យាបាលណាមួយឡើយ។.

សរសេរ និងពិនិត្យផ្នែកវេជ្ជសាស្ត្រដោយ៖ វេជ្ជបណ្ឌិត សូរ៉ាវី វីរ៉ាសូផូន (វេជ្ជបណ្ឌិត ប៉ុម) — អ្នកជំនាញខាងប្រព័ន្ធទឹកនោមដែលមានវិញ្ញាបនបត្រពីក្រុមប្រឹក្សាភិបាល ទីស្នាក់ការកណ្តាលមន្ទីរពេទ្យបាងកក។ អ្នកស្រាវជ្រាវអន្តរជាតិ៖ មហាវិទ្យាល័យវេជ្ជសាស្ត្របៃឡ័រ (សហរដ្ឋអាមេរិក) · សាកលវិទ្យាល័យជូនថេនដូ (ជប៉ុន) · មន្ទីរពេទ្យអនុស្សាវរីយ៍ឆាងហ្គុង (តៃវ៉ាន់)។.

វេជ្ជបណ្ឌិត Soarawee Weerasopone

លោកវេជ្ជបណ្ឌិត សូរ៉ាវី វីរ៉ាសូផូន (លោកវេជ្ជបណ្ឌិត ប៉ុម) គឺជាគ្រូពេទ្យឯកទេសខាងប្រព័ន្ធទឹកនោមដែលមានវិញ្ញាបនបត្រនៅទីស្នាក់ការកណ្តាលមន្ទីរពេទ្យបាងកក ដែលមានជំនាញខាងសុខភាពបុរស ការវះកាត់ដោយមនុស្សយន្ត (ប្រព័ន្ធដាវីនស៊ី) និងការព្យាបាលគ្រួសក្នុងតម្រងនោម។ លោកបានបញ្ចប់អាហារូបករណ៍អន្តរជាតិនៅមហាវិទ្យាល័យវេជ្ជសាស្ត្របៃឡ័រ (សហរដ្ឋអាមេរិក) មន្ទីរពេទ្យសាកលវិទ្យាល័យជូនថេនដូ (ជប៉ុន) និងមន្ទីរពេទ្យអនុស្សាវរីយ៍ឆាងហ្គុង (តៃវ៉ាន់)។ ខ្លឹមសារវេជ្ជសាស្ត្រទាំងអស់នៅលើគេហទំព័រនេះត្រូវបានសរសេរ និងពិនិត្យដោយលោកវេជ្ជបណ្ឌិត សូរ៉ាវី ដោយផ្អែកលើបទពិសោធន៍គ្លីនិក និងការបណ្តុះបណ្តាលអន្តរជាតិរបស់លោក។.