最終更新日: 2026年5月18日
Number one problem which causes patients extremely upset in my office it is the possibility of the HIV’s transmission after an unsafe sexual intercourse occurred. People have known on how to protect the HIV infection by wearing the condom while have sex. Has anyone know that circumcision might has protective effect on this? Curious? let’s get start.

I got a solid information on male circumcision which is very advantage in medical conditions who practicing in phimosis – a congenital narrowing of the opening of the foreskin so that it cannot be retracted – and bacterial infected of the foreskin. I’m so thrill to explain you on how the circumcision will take advantage in the protecting and reducing the HIV’s transmission rate while an unsafe sexual have lure.
Several quality literatures have shown from 60%–70% good chance in term of reducing an HIV transmission rate, especially for men who have done circumcision comparing to men who have not. This point has been deriving all researchers tried to figure out the best answer – the foreskin is a major part of an HIV transmission.

3 Reasons why foreskin removal reduces HIV transmission risk.
- The HIV’s primary target cells are concentrated in the foreskin
- Strong evidence shows that the primary target cell for HIV is “Langerhans cells” – natural human white blood cells that are predominant in the inner foreskin tissue. Male circumcision removes this high-risk tissue entirely.
- The inner foreskin has a thinner, more vulnerable skin barrier
- HIV transmission occurs when the virus contacts vaginal secretions through the skin. The inner foreskin contains fewer keratinized (protective) skin layers than the rest of the penile skin, making it significantly more permeable to viral entry.
- The inner foreskin is also prone to micro-abrasions and tears during sexual activity, further increasing HIV transmission risk at these sites.
- The normal flora of the inner foreskin promotes HIV transmission
- An interesting literature highlights that normal flora living on the inner foreskin produce pro-inflammatory agents that facilitate easier contact between HIV and Langerhans cells, effectively amplifying transmission risk.
It seems like living without the foreskin gains a lot more protective benefits than previously understood. Circumcision alone is not a substitute for condom use, but it offers significant additional protection. Always consult with your trusted urologist for personalized advice.
ご不明な点がございましたら、テキストでお問い合わせください 私 または、信頼できる泌尿器科医に詳細をお問い合わせください。
If you are considering adult circumcision for medical, protective, or personal reasons, Dr. Soarawee Weerasopone offers specialist consultations at Bangkok Hospital Headquarters. 診療をご予約.
Frequently Asked Questions about Circumcision and HIV Prevention
Yes. Multiple high-quality studies have shown that male circumcision reduces the risk of HIV transmission by 60–70% in heterosexual men. The protective effect is attributed to the removal of the inner foreskin, which contains a high density of HIV-susceptible Langerhans cells, has a thinner skin barrier, and is prone to micro-tears during intercourse.
The inner foreskin tissue has three characteristics that make it particularly vulnerable to HIV. First, it is densely populated with Langerhans cells, which are the primary target cells for HIV entry. Second, it has fewer keratinized (protective) skin layers than other penile tissue, making it more permeable. Third, it is prone to abrasions and micro-tears during sexual activity, creating direct entry points for the virus.
No. Circumcision significantly reduces but does not eliminate HIV transmission risk. It should be considered a complementary preventive measure, not a replacement for condoms. The most effective strategy combines consistent condom use, circumcision, safe sexual behavior, and regular STI screening – especially for men in high-prevalence settings.
Beyond HIV, evidence suggests circumcision also reduces the risk of other sexually transmitted infections including HPV (human papillomavirus), genital herpes (HSV-2), and syphilis. It also significantly reduces the risk of phimosis, recurrent balanitis (foreskin infections), and penile cancer over a lifetime.
No. Adult circumcision provides the same protective benefits as circumcision performed earlier in life. The procedure can be safely performed under local anesthesia as an outpatient procedure. If you are considering circumcision for medical, protective, or personal reasons, a consultation with a urologist will help you assess the options and choose the most appropriate surgical technique.
**免責事項:** このコンテンツは、バンコク病院本部の認定泌尿器科医であるSoarawee Weerasopone博士によって作成およびレビューされました。教育目的のみのものであり、医学的アドバイスを構成するものではありません。いかなる医療処置を開始する前にも、必ず資格のある医療専門家にご相談ください。.
医学的に記述・監修: ソアラウィー・ウィーラソポーン医師(ポム医師) — バンコク病院本社 泌尿器科専門医。 国際フェロー:ベイラー医科大学(米国)、順天堂大学(日本)、長庚紀念医院(台湾)。.

ソアラウィー・ウィーラソポーン医師(ポム医師)は、バンコク病院本院の泌尿器科専門医で、男性医学、ロボット手術(ダヴィンチシステム)、腎結石治療を専門としています。ベイラー医科大学(米国)、順天堂大学医学部附属順天堂医院(日本)、長庚記念医院(台湾)での国際フェローシップを修了しています。このサイトのすべての医療コンテンツは、ソアラウィー医師の臨床経験と国際的なトレーニングに基づいて、同医師によって作成・監修されています。.


これは役立つ情報です。ポミー博士、ありがとう!
どういたしまして!スティーブン博士。