Last updated: March 6, 2024
It is very compromised as we are a doctor that should have keep ourselves an up to date for medical practicing, especially when dealing with sexually transmitted diseases (STDs) infection, because all these microorganisms are continuously evolving against antibiotic and turn resistant to the standard treatment over time. Precisely treatment with antibiotic strength and adequate duration will completely help to eradicate STDs in infection.

Centers for Disease Control and Prevention (CDC) is an American healthcare organization which play major role in global medical practice and frequently launches varieties of clinical practice guidelines. Our topic today will be a 2020 updated from CDC treatment guideline on Gonococcal infection. (I have been mentioned the clinical symptom of Gonorrhea in this link)

First line Gonorrhea infection treatment of cervix, urethra or rectum:
- Ceftriaxone 500 mg intramuscular injection as a single dose (Body weight < 150 kg)
- Ceftriaxone 1-gram intramuscular injection as a single dose (Body weight > 150 kg)
Alternative Gonorrhea infection treatment of cervix, urethra or rectum:
- Gentamicin 240 mg intramuscular injection as single dose + Azithromycin 2 gram orally as single dose
- Cefixime 800 mg orally as single dose

In case common co-infection, Chlamydia cannot be excluded
- Doxycycline 100 mg orally twice a day for 7 days
In case of rare condition, Ceftriaxone treatment failure, specimen culture is recommended for accurately antibiotic selection. Any questions, you can discuss with your trusted Urologist or it would be my honor if you can text me. See you in next topic!
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Topics on Sexually Transmitted diseases
Medically written & reviewed by: Dr. Soarawee Weerasopone (Dr. Pom) — Board-Certified Urologist, Bangkok Hospital Headquarters. International Fellow: Baylor College of Medicine (USA) · Juntendo University (Japan) · Chang Gung Memorial Hospital (Taiwan).

Dr. Soarawee Weerasopone (Dr. Pom) is a board-certified urologist at Bangkok Hospital Headquarters, specializing in Men’s Health, Robotic Surgery (Da Vinci System), and Kidney Stone treatment. He has completed international fellowships at Baylor College of Medicine (USA), Juntendo University Hospital (Japan), and Chang Gung Memorial Hospital (Taiwan). All medical content on this site is written and reviewed by Dr. Soarawee based on his clinical experience and international training.






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