Zuletzt aktualisiert: 15. August 2026

For men with erectile dysfunction that has not responded to medication, a penile prosthesis can be a life-changing operation. The shadow hanging over it is Infektion. During my time as a Research Scholar and Clinical Observer at the Scott Department of Urology, Baylor College of Medicine, working alongside Professor Mohit Khera, I have seen how serious that complication is: an infected device usually has to be removed and replaced at a second operation.

A note on who this article is for. Most of what follows is written for colleagues — targets, thresholds and operating-theatre detail. I have left it that way deliberately, because patients are entitled to see what their surgeon is actually thinking about rather than a simplified version. If you are reading this as a patient, the practical section near the end is the part that concerns you, and nothing here should be acted on without your own doctor.

To push the risk down further, urologists have been looking toward colleagues in orthopaedic surgery. Why? Because orthopaedic surgeons have been refining implant success for decades. Whether it is a titanium hip or a silicone penile cylinder, the body’s biological response to a foreign object is remarkably similar. By adopting the protocols used to prevent periprosthetic joint infections, we can improve the safety and longevity of penile implants.

Visuelle Zusammenfassung als Infografik von Dr. Soarawee Weerasopone – 6 Lektionen aus der orthopädischen Chirurgie, angewendet auf die Penisprothesen-Chirurgie zur Infektionsprävention, einschließlich Blutzuckerkontrolle, Dekolonisierung, Raucherentwöhnung und sterile Barriere-Techniken
Preventing penile prosthetic infections — lessons from orthopaedic surgery

Why Borrow from Orthopaedic Surgery?

Below is a comparison of the most useful orthopaedic strategies and how they translate into penile prosthesis surgery. Worth saying plainly: most of these are extrapolated from joint replacement rather than proven in penile implant trials. The biology is close enough to be persuasive, and that is not the same as proof.

StrategieOrthopaedic applicationPotential benefit in urology
Glycaemic controlHbA1c < 7%; glucose < 180 mg/dLSchnellere Wundheilung; reduzierter Bakteriennährstoff
DecolonisationNasal mupirocin & chlorhexidine washesRemoves carriage from the patient’s own skin and nose
Smoking cessation6-wöchige präoperative Pause; Cotinin-TestungStellt die Blutzufuhr und Sauerstoffversorgung des Operationsbereichs wieder her
Sterile barriersDoppelhandschuhe und Kittel-Handschuh-VersiegelungPrevents microscopic contamination from the surgical team
Theatre disciplineStündlicher Wechsel von Saugspitzen; geringes VerkehrsaufkommenReduziert luftübertragene Bakterien im Operationssaal
Five orthopaedic infection-prevention strategies and their application to penile prosthesis surgery.

1. Preoperative Optimisation: Winning Before the First Incision

In orthopaedics, surgery is the culmination of a preparation phase. The pre-habilitation of a patient matters as much as the operation.

Reifer Mann verpflichtet sich zur Raucherentwöhnung vor einer Penisprothesenoperation – die aus der Orthopädie abgeleitete 6-Wochen-Regel und die präoperative Lebensstilvorbereitung sind unerlässlich, um das Infektionsrisiko zu senken und die Wundheilung bei chirurgischen Eingriffen im Bereich der Männergesundheit zu verbessern.

Medical and Glycaemic Control

Patients with diabetes are at higher risk of infection, because high blood sugar impairs the immune system’s ability to fight bacteria.

Lifestyle: Smoking and Alcohol

Rauchen ist vielleicht der größte Feind der Wundheilung. Nikotin verengt die Blutgefäße, wodurch die Operationsstelle von dem für die Gewebereparatur benötigten Sauerstoff und den Nährstoffen abgeschnitten wird.

Decolonisation: Clearing the Pathogen Reservoir

Bacteria live harmlessly on skin and in the nose until an incision provides a doorway.

These are prescribed and timed by the surgical team, not bought and started independently. Mupirocin is a prescription antibiotic, and using it without indication contributes to resistance; chlorhexidine washes have their own instructions and can irritate skin. If your operation is being planned, ask what your hospital’s protocol is rather than assembling one yourself.

Ernährungsunterstützung

A malnourished body does not heal well. Markers used to judge whether a patient is biologically ready for an implant include:

2. Intraoperativer Vigilanz: Absicherung des sterilen Feldes

The operating theatre is a controlled environment, but not a perfect one. Orthopaedics has developed near-theatrical levels of precision to maintain sterility — standards urology is actively adopting.

Sterile Operationssaaleinrichtung für Penisprothesenchirurgie — strenge intraoperative Protokolle, einschließlich doppelten Handschuhen, Hautvorbereitung mit Chlorhexidin-Alkohol und Kontrolle des OP-Verkehrs, reduzieren das Infektionsrisiko, von Dr. Soarawee Weerasopone im Bangkok Hospital

Skin Preparation and Hand Hygiene

Umweltmanagement

3. Postoperative Versorgung: Das kritische Erholungsfenster

Once the operation is finished the job is not. The first weeks are the most vulnerable time for a new prosthesis.

Langfristige Gesundheit und Hygiene

An infection can occur months or even years later if bacteria from elsewhere in the body enter the bloodstream. Good general and dental health is therefore part of protecting any internal prosthesis. Note, though, that this does nicht mean routinely taking antibiotics before dental treatment: that practice has fallen out of favour for prosthetic implants generally, and it is a question for your urologist rather than an assumption. What is worth doing is telling your dentist that you have an implant.

What Any of This Asks of You

Stripped of the thresholds, the patient’s side of this list is short:

Those warning signs, briefly: fever or chills, spreading redness or discharge, pain that increases after the first few days instead of settling, a tense or rapidly swelling scrotum, inability to pass urine, or any part of the device becoming visible — all of which need to be reported the same day rather than at the next appointment. And an implant infection can also appear months later as pain that never quite settles. Reporting early is often what decides whether the device can be saved. The longer history of how implant infection was brought under control covers this in more detail.

Das Endergebnis

The path to better outcomes in urology is often paved with the successes of other surgical fields. By viewing the penile prosthesis through the lens of orthopaedic arthroplasty, we move toward a standard of care where infection is uncommon. Uncommon, not impossible — the risk remains higher in men with diabetes, in men who are immunosuppressed, and in revision surgery, and no protocol removes it entirely.

For men exploring a penile prosthesis as a treatment for erektile Dysfunktion, choosing a surgeon who follows rigorous infection-prevention protocols is one of the more consequential decisions available to you — alongside understanding that the operation itself is irreversible. These protocols are applied as standard rather than as optional extras; see how they fit into the wider Penile Prothesenchirurgie, von der Geräteauswahl bis zur Langzeitnachsorge.

If you are considering penile prosthesis surgery and would like a full evaluation, Dr. Soarawee Weerasopone consults at Bangkok Hospital Hauptsitz and at Samitivej Sriracha Hospital, Chonburi — 088-022-1445.

Bangkok Hospital Telemedicine is available for patients who cannot attend in person, including international patients — arrange it in advance by email to the Urology department at bhquro@bdms.co.th. It suits an initial discussion and planning the preparation described above; assessment and surgery require an in-person visit. Samitivej Sriracha is in-person only.

Häufig gestellte Fragen zu Penisimplantat-Infektionen

Wie häufig ist eine Infektion nach einer Penisprothesen-Operation?

Uncommon in experienced hands, thanks to antibiotic-coated devices, chlorhexidine-alcohol skin preparation and refined technique. It has not been eliminated, and the risk is higher in men with diabetes, in men who are immunosuppressed, and in revision surgery. A single infection matters disproportionately because it usually means removing the device and replacing it at a second operation.

Warum ist Diabetes ein so erheblicher Risikofaktor?

High blood sugar impairs white blood cell function, weakens the immune response and slows wound healing. Achieving an HbA1c below 7% before surgery and keeping postoperative glucose below 180 mg/dL reduces that risk, and is worth the weeks it takes to arrange.

Wie lange sollte ich vor einer Penisprothesenoperation mit dem Rauchen aufhören?

Following orthopaedic practice, at least six weeks before surgery. Nicotine constricts blood vessels and reduces oxygen delivery to healing tissue, increasing the risk of wound complications and device infection. If six weeks is not possible, stopping for any period beforehand is still better than not stopping.

Should I buy antiseptic wash or nasal ointment before my operation?

No — ask your surgical team what their protocol is instead. Mupirocin is a prescription antibiotic and using it without indication contributes to resistance, and antiseptic washes have specific instructions and timing. Assembling a protocol from an article is not the same as following the one your hospital uses.

Can dental problems cause a penile prosthesis infection?

Bacteria from a significant dental infection can enter the bloodstream and, in principle, settle on any prosthetic device. Good oral health is therefore worth maintaining, and your dentist should know you have an implant. This is not the same as routinely taking antibiotics before dental treatment, which is no longer standard practice for prosthetic implants — ask your urologist rather than assuming either way.

What should I watch for after the operation?

Fever or chills, spreading redness or discharge, pain increasing after the first few days rather than settling, a tense or rapidly swelling scrotum, inability to pass urine, or any part of the device becoming visible. Report these the same day. An implant infection can also appear months later as pain that never quite settles.

Disclosure: Dr. Soarawee Weerasopone has received travel and accommodation support from Boston Scientific for prosthetic surgery training workshops. He receives no payment from any manufacturer for this article, and device selection for patients is based on clinical factors.

Haftungsausschluss: This content is written and reviewed by Dr. Soarawee Weerasopone, a board-certified urologist at Bangkok Hospital Headquarters. It is intended for educational purposes only and does not constitute medical advice. Thresholds and protocols described here are for clinical reference and should not be self-applied. No advice, diagnosis or prescription is given through personal messaging channels or social media. Always consult a qualified healthcare professional before starting or changing any medical treatment.

Medizinisch verfasst & überprüft von: Dr. Soarawee Weerasopone (Dr. Pom) – Fachärztin für Urologie, Bangkok Hospital Headquarters, seit 2016 in urologischer Praxis tätig. Fellowship: Roboterchirurgie, Chang Gung Memorial Hospital, Taiwan (2019) · Hospitation: Endourologie, Juntendo University Hospital, Tokio (2022) · Forschungsstipendiatin & Klinische Hospitantin, Scott Department of Urology, Baylor College of Medicine, USA (2025–2026).

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