{"id":4244,"date":"2021-10-08T08:00:00","date_gmt":"2021-10-08T01:00:00","guid":{"rendered":"https:\/\/drsoaraweeurology.com\/?p=4244"},"modified":"2026-05-18T09:51:02","modified_gmt":"2026-05-18T02:51:02","slug":"%e6%a2%85%e6%af%92-%e6%ad%a3%e7%a1%ae%e7%9a%84%e6%96%b9%e5%bc%8f-%e5%a4%84%e7%90%86","status":"publish","type":"post","link":"https:\/\/drsoaraweeurology.com\/zh\/2021\/10\/08\/syphilis-correct-way-deal-with\/","title":{"rendered":"\u6885\u6bd2\uff1a\u6211\u4eec\u5904\u7406\u7684\u6b63\u786e\u65b9\u6cd5\u3002\ufffc"},"content":{"rendered":"\n<div class=\"wp-block-columns coblocks-author-columns has-background is-layout-flex wp-container-core-columns-is-layout-52275889 wp-block-columns-is-layout-flex\" style=\"background-color:#8C8C971A;padding-top:2.5rem;padding-right:2.5rem;padding-bottom:2.5rem;padding-left:2.5rem\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<figure class=\"wp-block-image size-full is-style-rounded\"><img data-recalc-dims=\"1\" fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"800\" data-attachment-id=\"7037\" data-permalink=\"https:\/\/drsoaraweeurology.com\/zh\/new-photo-2024\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" data-orig-size=\"800,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=800%2C800&#038;ssl=1\" alt=\"Best Urologist working in Chonburi and Cambodia\" class=\"wp-image-7037\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?w=800&amp;ssl=1 800w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=768%2C768&amp;ssl=1 768w, 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1.255.564 2.073.564.8 0 1.536-.213 2.105-.603.57-.39.94-.916 1.175-1.65.076-.235.135-.558.177-.93a15.4 15.4 0 0 0 .063-1.207v-.512a.27.27 0 0 0-.273-.273h-2.95a.27.27 0 0 0-.274.273v.785c0 .228.0.343.273.343h1.337c.094 0 .14.045.14.137 0 .61-.063 1.043-.155 1.318-.182.546-.7 1.018-1.683 1.018-.654 0-1.135-.114-1.475-.356-.34-.244-.55-.585-.658-1.024a3.797 3.797 0 0 1-.111-.43 5.515 5.515 0 0 1-.06-.51 19.85 19.85 0 0 1-.025-.726c-.004-.28-.004-.628-.004-1.045 0-.418 0-.766.004-1.046a19.85 19.85 0 0 1 .025-.726 5.475 5.475 0 0 1 .06-.51 3.785 3.785 0 0 1 .111-.43c.108-.44.318-.78.658-1.024.34-.243.82-.357 1.475-.357.6 0 1.064.078 1.413.293.347.215.595.515.74.91.063.155.166.21.31.156l.967-.4c.15-.058.187-.18.13-.32a3.025 3.025 0 0 0-1.262-1.452C21.12.218 20.428.0 19.586 0zM8.512 4.32c-2.7 0-4.066.997-4.066 3.06v.04c0 1.92.992 2.83 3.046 2.83 1.27 0 2.038-.39 2.385-1.05h.13l.067.51c.04.2.207.34.41.34h.99V7.95c0-2.59-1.06-3.63-2.962-3.63zm-.18 1.61c1.118 0 1.628.56 1.628 1.86v.4l-1.65.16c-1.35.13-1.86.46-1.86 1.13v.04c0 .67.41 1.06 1.45 1.06.85 0 1.55-.32 1.93-.84.04-.06.13-.07.18-.02.05.03.07.1.07.16v.43c0 .26.13.42.34.42h1.05c.21 0 .34-.16.34-.42v-3.6c0-1.94-1.13-2.83-3.46-2.83-1.94 0-3.07.86-3.4 2.04l1.55.45c.18-.69.6-1.04 1.83-1.04zM2.135 16.314c-.587 0-1.066-.156-1.434-.469-.367-.312-.618-.704-.752-1.176-.034-.124-.061-.232-.082-.327a3.794 3.794 0 0 1-.044-.366 8.83 8.83 0 0 1-.022-.547C0 13.221 0 12.985 0 12.704c0-.281 0-.515.001-.704a8.81 8.81 0 0 1 .022-.547 3.802 3.802 0 0 1 .044-.366c.02-.094.048-.203.082-.328.134-.471.385-.864.752-1.176.368-.313.847-.469 1.434-.469.477 0 .892.087 1.246.262.353.175.622.443.806.804.044.083.083.157.117.222.034.066.069.144.105.235.022.054.011.099-.034.135l-.66.292c-.045.027-.082.013-.112-.045a4.043 4.043 0 0 0-.155-.27 1.247 1.247 0 0 0-.49-.495c-.225-.131-.522-.196-.892-.196-.402 0-.726.064-.972.193-.247.13-.422.302-.527.518-.027.045-.054.099-.082.16a1.39 1.39 0 0 0-.067.197 2.46 2.46 0 0 0-.05.282 5.51 5.51 0 0 0-.033.43c-.008.17-.013.376-.013.617 0 .242.005.448.013.618.008.17.02.314.034.43.013.117.03.21.05.282.02.072.042.137.066.197.105.216.28.39.527.518.246.13.57.193.972.193.4 0 .714-.07.94-.21.227-.14.394-.346.503-.617a2.43 2.43 0 0 0 .104-.395c.018-.123.027-.282.027-.477V13.2H2.34c-.04 0-.06-.02-.06-.062v-.5c0-.04.02-.062.06-.062h1.812c.04 0 .062.02.062.06v.5c0 .156-.005.296-.014.422a4.71 4.71 0 0 1-.04.342 1.732 1.732 0 0 1-.064.262c-.13.523-.402.913-.815 1.17-.413.255-.95.382-1.61.382z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/orcid.org\/0009-0004-8387-3559\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"ORCID iD\"\n     aria-label=\"View ORCID Profile\"\n     style=\"text-decoration: none; color: #A6CE39; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M12 0C5.372 0 0 5.372 0 12s5.372 12 12 12 12-5.372 12-12S18.628 0 12 0zM7.369 4.378c.525 0 .947.431.947.947 0 .525-.422.947-.947.947-.525 0-.946-.422-.946-.947 0-.525.421-.947.946-.947zm-.722 3.038h1.444v10.041H6.647V7.416zm3.562 0h3.9c3.712 0 5.344 2.653 5.344 5.025 0 2.578-2.016 5.025-5.325 5.025h-3.919V7.416zm1.444 1.303v7.444h2.297c3.272 0 4.022-2.484 4.022-3.722 0-2.016-1.284-3.722-4.097-3.722h-2.222z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/scholar.google.com\/citations?user=lTgsRMUAAAAJ&#038;hl=en\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"Google Scholar\"\n     aria-label=\"View Google Scholar Profile\"\n     style=\"text-decoration: none; color: #4285F4; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M5.242 13.769L0.5 9.5 12 1l11.5 8.5-4.742 4.269C17.548 11.249 14.978 9.5 12 9.5c-2.977 0-5.548 1.748-6.758 4.269zM12 10a7 7 0 1 0 0 14 7 7 0 0 0 0-14z\"\/>\n    <\/svg>\n  <\/a>\n  \n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Many syphilis-positive patients come to see me at my Urology office \u2014 some are na\u00efve cases while others are treatment-failure cases from other clinics. This topic will explain how we correctly manage syphilis infection and how to confirm successful treatment.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Urology center Bangkok hospital Thailand\u00a0<a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" target=\"_blank\" rel=\"noreferrer noopener\">Booking online<\/a>\u00a0<a href=\"tel:02-310-3009\">02-310-3009<\/a>\u00a0<a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a><\/li>\n\n\n\n<li>Samitivej Sriracha hospital Chonburi&nbsp;<a href=\"tel:088-022-1445\">088-022-1445<\/a><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4257\" data-permalink=\"https:\/\/drsoaraweeurology.com\/zh\/2021\/10\/08\/syphilis-correct-way-deal-with\/upset-patient\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;Freepik Company S.L. - www.freepik.com&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Fail-to-treat Syphilis infection at local clinic is happened frequently.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Fail-to-treat Syphilis infection at local clinic is happened frequently.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Syphilis treatment failure\" class=\"wp-image-4257\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Upset-patient.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Treatment failure of syphilis at local clinics is not uncommon.<\/figcaption><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">CDC 2015 <a href=\"https:\/\/www.nycptc.org\/x\/Syphilis_Monograph_2019_NYC_PTC_NYC_DOHMH.pdf\">Syphilis treatment recommendation<\/a><\/h4>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4255\" data-permalink=\"https:\/\/drsoaraweeurology.com\/zh\/2021\/10\/08\/syphilis-correct-way-deal-with\/young-doctor-is-holding-hypodermic-syringe-with-vaccine-vial-rubber-gloves-on-gray-background\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;13&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;Canon EOS 5D Mark III&quot;,&quot;caption&quot;:&quot;Young doctor is  holding  hypodermic syringe with  vaccine vial  rubber gloves on gray background.&quot;,&quot;created_timestamp&quot;:&quot;1586013043&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;200&quot;,&quot;iso&quot;:&quot;100&quot;,&quot;shutter_speed&quot;:&quot;0.01&quot;,&quot;title&quot;:&quot;Young doctor is  holding  hypodermic syringe with  vaccine vial  rubber gloves on gray background.&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Benzathine Penicillin G intramuscular injection is considered as first line treatment.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Benzathine Penicillin G intramuscular injection is considered as first line treatment.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Benzathine Penicillin G syphilis injection\" class=\"wp-image-4255\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/Pen-injection.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Benzathine Penicillin G intramuscular injection is considered the first-line treatment.<\/figcaption><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Treatment regimens\n\n<ul class=\"wp-block-list\">\n<li>Benzathine Penicillin G intramuscular injection \u2014 FIRST-LINE regimen<\/li>\n\n\n<li>Oral Doxycycline or Tetracycline \u2014 ALTERNATIVE regimens for penicillin-allergic patients<\/li>\n<\/ul>\n<\/li>\n\n\n<li>Patient education\n\n<ul class=\"wp-block-list\">\n<li>Avoid all sexual contact (including oral sex) until treatment is complete and all symptoms have resolved<\/li>\n\n\n<li>Wait at least 7 days after completing treatment and until all lesions are fully healed before resuming sexual activity<\/li>\n\n\n<li>Sexual partners must seek medical evaluation and confirm syphilis-free status before resuming contact<\/li>\n\n\n<li>Be aware of the Jarisch-Herxheimer Reaction: a fever, rash, malaise, myalgia, nausea, and headache occurring within 24 hours of the first treatment dose. This reaction is caused by endotoxins released from dying syphilis bacteria and resolves safely within 24 hours \u2014 it is not an allergic reaction<\/li>\n\n\n<li>Co-testing for HIV, Gonorrhea, and Chlamydia is strongly recommended in all syphilis cases<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4256\" data-permalink=\"https:\/\/drsoaraweeurology.com\/zh\/2021\/10\/08\/syphilis-correct-way-deal-with\/bare-human-feet-sticking-out-from-the-bed\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.8&quot;,&quot;credit&quot;:&quot;Anna Bizon&quot;,&quot;camera&quot;:&quot;NIKON D3X&quot;,&quot;caption&quot;:&quot;Bare human feet sticking out from the bed&quot;,&quot;created_timestamp&quot;:&quot;1424441944&quot;,&quot;copyright&quot;:&quot;Gpoint Studio&quot;,&quot;focal_length&quot;:&quot;36&quot;,&quot;iso&quot;:&quot;100&quot;,&quot;shutter_speed&quot;:&quot;0.01&quot;,&quot;title&quot;:&quot;Bare human feet sticking out from the bed&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Avoid sexual activity is recommended during the treatment.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Avoid sexual activity is recommended during the treatment.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Avoid sexual activity syphilis treatment\" class=\"wp-image-4256\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/SI.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Avoiding sexual activity is recommended during syphilis treatment.<\/figcaption><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Follow-up plan\n\n<ul class=\"wp-block-list\">\n<li>VDRL blood test is used to monitor treatment success<\/li>\n\n\n<li>A 4-fold decline in VDRL titer is considered a marker of successful treatment<\/li>\n\n\n<li>VDRL typically turns negative 6\u201312 months after successful syphilis treatment<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4254\" data-permalink=\"https:\/\/drsoaraweeurology.com\/zh\/2021\/10\/08\/syphilis-correct-way-deal-with\/closeup-of-blood-tube-test-2\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;Closeup of blood tube test&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;Rawpixel Ltd.&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;500&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;Closeup of blood tube test&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"VDRL blood test is the tool we use for tracking treatment success.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;VDRL blood test is the tool we use for tracking treatment success.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?resize=800%2C533&#038;ssl=1\" alt=\"VDRL blood test syphilis monitoring\" class=\"wp-image-4254\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/10\/VDRL-test.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">VDRL blood test is the tool we use for tracking syphilis treatment success.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Any questions, you can discuss with your trusted urologist.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You can visit my homepage <a href=\"https:\/\/drsoaraweeurology.com\/\">here<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions About Syphilis Treatment<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">What is the first-line treatment for syphilis?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The first-line treatment for syphilis per CDC guidelines is Benzathine Penicillin G administered as an intramuscular injection. The dose and number of injections depend on the stage of infection \u2014 early syphilis (primary, secondary, or early latent) requires a single injection, while late latent or tertiary syphilis requires 3 weekly injections. For patients allergic to penicillin, oral Doxycycline or Tetracycline are the recommended alternatives.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What is the Jarisch-Herxheimer reaction in syphilis treatment?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The Jarisch-Herxheimer reaction is a systemic inflammatory response that occurs within 24 hours of the first syphilis treatment dose. It is caused by endotoxins released from dying Treponema pallidum bacteria and presents with fever, generalized rash, malaise, myalgia, nausea, vomiting, and headache. The reaction is not an allergic response to penicillin and resolves safely within 24 hours without requiring cessation of treatment. Patients should be warned to expect this reaction.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">How do we know syphilis treatment was successful?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment success is monitored using serial VDRL blood tests. A 4-fold decline in VDRL titer (e.g., from 1:32 to 1:8) indicates successful treatment response. The VDRL typically becomes negative within 6\u201312 months after completing treatment for early syphilis. Persistent or rising titers may indicate treatment failure or re-infection, requiring clinical re-evaluation and repeat treatment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you have been diagnosed with syphilis or have concerns about a sexually transmitted infection, Dr. Soarawee Weerasopone offers specialist consultations at Bangkok Hospital Headquarters. <a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\">Book a Consultation<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> This content is written and reviewed by Dr. Soarawee Weerasopone, a board-certified urologist at Bangkok Hospital Headquarters. It is intended for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any medical treatment.<\/p>\n\n\n\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the first-line treatment for syphilis?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Benzathine Penicillin G intramuscular injection per CDC guidelines. Dosing depends on stage: single injection for early syphilis, 3 weekly injections for late latent\/tertiary. Doxycycline or Tetracycline are alternatives for penicillin-allergic patients.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the Jarisch-Herxheimer reaction in syphilis treatment?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A systemic reaction from endotoxins released by dying syphilis bacteria, occurring within 24 hours of first treatment. Symptoms include fever, rash, malaise, myalgia, and headache. It is not a penicillin allergy and resolves safely within 24 hours.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How do we know syphilis treatment was successful?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"A 4-fold decline in VDRL titer indicates successful treatment. VDRL typically becomes negative within 6-12 months after early syphilis treatment. Persistent or rising titers suggest treatment failure or re-infection requiring re-evaluation.\"\n      }\n    }\n  ]\n}\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Many syphilis-positive patients come to see me at my Urology office \u2014 some are na\u00efve cases while others are treatment-failure cases from other clinics. This topic will explain how we correctly manage syphilis infection and how to confirm successful treatment. CDC 2015 Syphilis treatment recommendation Any questions, you can discuss with your trusted urologist. You [&hellip;]<\/p>\n","protected":false},"author":185281453,"featured_media":10102,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"Syphilis treatment guide: Benzathine Penicillin G first-line, Jarisch-Herxheimer reaction explained, and VDRL monitoring for treatment success. 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