{"id":4629,"date":"2022-01-14T08:00:00","date_gmt":"2022-01-14T01:00:00","guid":{"rendered":"https:\/\/drsoaraweeurology.com\/?p=4629"},"modified":"2026-08-28T03:32:30","modified_gmt":"2026-08-27T20:32:30","slug":"%e0%b9%82%e0%b8%a3%e0%b8%84%e0%b8%96%e0%b8%b8%e0%b8%87%e0%b8%99%e0%b9%89%e0%b8%b3%e0%b8%94%e0%b8%b5-%e0%b9%84%e0%b8%95-%e0%b9%82%e0%b8%a3%e0%b8%84","status":"publish","type":"post","link":"https:\/\/drsoaraweeurology.com\/th\/2022\/01\/14\/polycystic-kidney-disease\/","title":{"rendered":"Polycystic Kidney Disease: What It Means, and What Can Now Be Done"},"content":{"rendered":"\n<div class=\"wp-block-columns coblocks-author-columns has-background is-layout-flex wp-container-core-columns-is-layout-52275889 wp-block-columns-is-layout-flex\" style=\"background-color:#8C8C971A;padding-top:2.5rem;padding-right:2.5rem;padding-bottom:2.5rem;padding-left:2.5rem\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<figure class=\"wp-block-image size-full is-style-rounded\"><img data-recalc-dims=\"1\" fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"800\" data-attachment-id=\"7037\" data-permalink=\"https:\/\/drsoaraweeurology.com\/th\/new-photo-2024\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" data-orig-size=\"800,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=800%2C800&#038;ssl=1\" alt=\"Best Urologist working in Chonburi and Cambodia\" class=\"wp-image-7037\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?w=800&amp;ssl=1 800w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=768%2C768&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=12%2C12&amp;ssl=1 12w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=600%2C600&amp;ssl=1 600w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=400%2C400&amp;ssl=1 400w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=200%2C200&amp;ssl=1 200w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:75%\">\n<p class=\"wp-block-paragraph\"><strong><a href=\"https:\/\/drsoaraweeurology.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">Soarawee Weerasopone, Urologist<\/a><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" target=\"_blank\" rel=\"noreferrer noopener\">Bangkok hospital Headquarter, Bangkok<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><a href=\"tel:+66880221445\" target=\"_blank\" rel=\"noreferrer noopener\">Samitivej Sriracha Hospital \u2014 Urology department: <strong>088-022-1445<\/strong><\/a><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link has-background-background-color has-text-color has-background has-link-color has-small-font-size has-custom-font-size wp-element-button\" href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" style=\"color:#1b4965\" target=\"_blank\" rel=\"noreferrer noopener\">Book a Consultation<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<ul class=\"wp-block-social-links aligncenter has-normal-icon-size is-style-default 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C7.947,6.93,8.004,7.642,7.52,7.699c0,0-0.487,0.057-1.029,0.085l3.274,9.739l1.968-5.901l-1.401-3.838 C9.848,7.756,9.389,7.699,9.389,7.699C8.904,7.67,8.961,6.93,9.446,6.958c0,0,1.484,0.114,2.368,0.114 c0.94,0,2.397-0.114,2.397-0.114c0.485-0.028,0.542,0.684,0.057,0.741c0,0-0.488,0.057-1.029,0.085l3.249,9.665l0.897-2.996 C17.841,13.284,18.069,12.316,18.069,11.546z M19.889,7.686c0.039,0.286,0.06,0.593,0.06,0.924c0,0.912-0.171,1.938-0.684,3.22 l-2.746,7.94c2.673-1.558,4.47-4.454,4.47-7.771C20.991,10.436,20.591,8.967,19.889,7.686z M12,22C6.486,22,2,17.514,2,12 C2,6.486,6.486,2,12,2c5.514,0,10,4.486,10,10C22,17.514,17.514,22,12,22z\"><\/path><\/svg><span class=\"wp-block-social-link-label screen-reader-text\">WordPress<\/span><\/a><\/li>\n\n<li class=\"wp-social-link wp-social-link-linkedin wp-block-social-link\"><a href=\"https:\/\/www.linkedin.com\/in\/soarawee-weerasopone\/\" class=\"wp-block-social-link-anchor\"><svg width=\"24\" height=\"24\" viewBox=\"0 0 24 24\" version=\"1.1\" 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.156-.005.296-.014.422a4.71 4.71 0 0 1-.04.342 1.732 1.732 0 0 1-.064.262c-.13.523-.402.913-.815 1.17-.413.255-.95.382-1.61.382z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/orcid.org\/0009-0004-8387-3559\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"ORCID iD\"\n     aria-label=\"View ORCID Profile\"\n     style=\"text-decoration: none; color: #A6CE39; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M12 0C5.372 0 0 5.372 0 12s5.372 12 12 12 12-5.372 12-12S18.628 0 12 0zM7.369 4.378c.525 0 .947.431.947.947 0 .525-.422.947-.947.947-.525 0-.946-.422-.946-.947 0-.525.421-.947.946-.947zm-.722 3.038h1.444v10.041H6.647V7.416zm3.562 0h3.9c3.712 0 5.344 2.653 5.344 5.025 0 2.578-2.016 5.025-5.325 5.025h-3.919V7.416zm1.444 1.303v7.444h2.297c3.272 0 4.022-2.484 4.022-3.722 0-2.016-1.284-3.722-4.097-3.722h-2.222z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/scholar.google.com\/citations?user=lTgsRMUAAAAJ&#038;hl=en\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"Google Scholar\"\n     aria-label=\"View Google Scholar Profile\"\n     style=\"text-decoration: none; color: #4285F4; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M5.242 13.769L0.5 9.5 12 1l11.5 8.5-4.742 4.269C17.548 11.249 14.978 9.5 12 9.5c-2.977 0-5.548 1.748-6.758 4.269zM12 10a7 7 0 1 0 0 14 7 7 0 0 0 0-14z\"\/>\n    <\/svg>\n  <\/a>\n  \n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Polycystic kidney disease is an inherited condition in which fluid-filled cysts form throughout both kidneys and slowly enlarge over decades, gradually crowding out working tissue. It affects somewhere between one in 500 and one in 4,000 people, men and women equally, and is the commonest inherited cause of kidney failure.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is usually silent in childhood and starts causing problems in the thirties and forties. Around half of those affected need dialysis or a transplant by about sixty \u2014 although, as below, that varies far more between individuals than a single figure suggests.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">This is primarily a <strong>kidney physician&#8217;s<\/strong> condition, managed jointly. A urologist deals with its mechanical complications \u2014 pain, bleeding, infection, stones \u2014 and with transplantation. Both matter, and neither replaces the other.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Urology center Bangkok hospital Thailand\u00a0<a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" target=\"_blank\" rel=\"noreferrer noopener\">Booking online<\/a>\u00a0<a href=\"tel:02-310-3009\">02-310-3009<\/a>\u00a0<a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a><\/li>\n\n\n\n<li>Samitivej Sriracha hospital Chonburi&nbsp;<a href=\"tel:088-022-1445\">088-022-1445<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Symptoms that are an emergency<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">This section was absent from the earlier version, and the first item on it is the most important thing on the page. In an emergency in Thailand, call <strong>1669<\/strong>.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>A sudden, severe headache \u2014 the worst you have ever had \u2014 particularly with neck stiffness, vomiting or altered consciousness.<\/strong> People with this condition have a higher rate of aneurysms in the blood vessels of the brain, and this presentation is treated as bleeding around the brain until proved otherwise. <strong>Go to an emergency department immediately.<\/strong><\/li>\n\n\n\n<li><strong>Fever with flank pain<\/strong> \u2014 an infected cyst, which is difficult to treat because many antibiotics do not penetrate cysts well, and which needs urgent assessment rather than an ordinary course of tablets.<\/li>\n\n\n\n<li><strong>Severe flank pain with heavy bleeding or clots<\/strong>, or bleeding with dizziness and a racing pulse.<\/li>\n\n\n\n<li><strong>Passing little or no urine<\/strong>, or rapidly worsening swelling and breathlessness.<\/li>\n\n\n\n<li><strong>Sudden severe abdominal pain<\/strong>, since cysts can rupture and diverticular problems are commoner in this condition.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"800\" data-attachment-id=\"4645\" data-permalink=\"https:\/\/drsoaraweeurology.com\/th\/2022\/01\/14\/polycystic-kidney-disease\/kidney-cyst-2\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?fit=800%2C800&amp;ssl=1\" data-orig-size=\"800,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;kidney Cyst disease and  Normal kidney.Vector illustrations&quot;,&quot;created_timestamp&quot;:&quot;1512818753&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;kidney Cyst&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Polycystic kidney disease is a state of several cystic lesions all over the kidney organ.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Polycystic kidney disease is a state of several cystic lesions all over the kidney organ.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?fit=800%2C800&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=800%2C800&#038;ssl=1\" alt=\"Kidney containing numerous cysts, characteristic of polycystic kidney disease\" class=\"wp-image-4645\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?w=800&amp;ssl=1 800w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=768%2C768&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=12%2C12&amp;ssl=1 12w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=400%2C400&amp;ssl=1 400w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/Cystic-kidney.jpg?resize=200%2C200&amp;ssl=1 200w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Cysts enlarge over decades, gradually displacing working kidney tissue.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">How it is inherited<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The earlier version described the condition as genetic without explaining the inheritance, which is what families most want to know.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The common adult form is <strong>autosomal dominant<\/strong>: <strong>each child of an affected parent has a one in two chance of inheriting it<\/strong>, regardless of sex, and it does not skip generations. A minority have no family history at all, the gene change having arisen new in them.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Two genes account for most cases, and which one matters: one is associated with earlier kidney failure than the other, which is part of why outcomes differ so widely between families. A separate, much rarer recessive form affects infants and behaves quite differently.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Screening relatives is a decision worth taking deliberately rather than by default \u2014 it has implications for insurance and for living-donor assessment, and it is normally discussed before testing rather than afterwards.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What it causes<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">In the kidneys<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>High blood pressure<\/strong> \u2014 the commonest problem, often appearing before kidney function declines at all, and the single most important thing to control because it drives the decline.<\/li>\n\n\n\n<li><strong>Flank pain<\/strong>, from a bleeding cyst (blood in the urine is the clue), an infected cyst (fever is the clue), a stone, or simply the weight of enlarged kidneys.<\/li>\n\n\n\n<li><strong>Kidney stones<\/strong>, in around one in five.<\/li>\n\n\n\n<li><strong>Urinary infections<\/strong>, including kidney infection \u2014 see <a href=\"https:\/\/drsoaraweeurology.com\/2021\/04\/02\/acute-pyelonephritis\/\">kidney infection<\/a>.<\/li>\n\n\n\n<li><strong>Declining kidney function<\/strong> over decades, ending in dialysis or transplantation in a substantial proportion.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Outside the kidneys \u2014 absent from the earlier version<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Brain aneurysms.<\/strong> Uncommon but the most serious association. Screening with a brain scan is not routine for everyone; it is recommended where there is <strong>a family history of aneurysm or of bleeding around the brain<\/strong>, and in certain occupations. If that applies to your family, raise it \u2014 it is the question most worth asking at your next appointment.<\/li>\n\n\n\n<li><strong>Cysts in the liver<\/strong>, which are very common, usually harmless, and often larger in women.<\/li>\n\n\n\n<li><strong>Heart valve abnormalities<\/strong>, usually mild.<\/li>\n\n\n\n<li><strong>Hernias and diverticular disease of the bowel.<\/strong><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4643\" data-permalink=\"https:\/\/drsoaraweeurology.com\/th\/2022\/01\/14\/polycystic-kidney-disease\/digital-blood-pressure-monitor-on-wooden-table-medical-electronic-tonometer-check-blood-pressure\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.8&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;NIKON D750&quot;,&quot;caption&quot;:&quot;Digital Blood Pressure Monitor on wooden table , Medical electronic tonometer check blood pressure&quot;,&quot;created_timestamp&quot;:&quot;1608192721&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;24&quot;,&quot;iso&quot;:&quot;500&quot;,&quot;shutter_speed&quot;:&quot;0.003125&quot;,&quot;title&quot;:&quot;Digital Blood Pressure Monitor on wooden table , Medical electronic tonometer check blood pressure&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Hypertension is the most common comorbidity of Polycystic kidney disease.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Hypertension is the most common comorbidity of Polycystic kidney disease.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Blood pressure measurement, the most important element of polycystic kidney disease management\" class=\"wp-image-4643\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2022\/01\/High-blood-pressure.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Blood pressure control does more to preserve kidney function than anything else available.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Treatment: what has changed<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The earlier version of this article said there is no treatment beyond controlling blood pressure and managing complications. <strong>That is out of date and has been corrected.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A drug now exists \u2014 <strong>tolvaptan<\/strong> \u2014 that slows the growth of the cysts and the decline in kidney function. It does not cure the condition and it does not suit everyone: it is for people whose disease is <strong>progressing rapidly<\/strong>, judged on kidney size, the rate of functional decline and age. It causes an enormous increase in thirst and urine output, which many find hard to live with, and it requires <strong>regular blood tests to monitor the liver<\/strong>, since liver injury is a recognised risk.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Whether it is appropriate is a nephrology decision. What matters here is that <strong>the question should be asked<\/strong> \u2014 a page saying nothing can be done leaves people not asking it.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">The rest of management<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Blood pressure control<\/strong>, tightly and from early on. Still the most effective intervention available.<\/li>\n\n\n\n<li><strong>Generous fluid intake and reduced salt<\/strong>, which may slow cyst growth and certainly helps the blood pressure and the stones.<\/li>\n\n\n\n<li><strong>Avoiding anti-inflammatory painkillers<\/strong> where possible \u2014 a practical point for a condition whose main symptom is pain, and one people are rarely told.<\/li>\n\n\n\n<li><strong>Prompt, adequate treatment of infections<\/strong>, with antibiotics chosen for their ability to penetrate cysts.<\/li>\n\n\n\n<li><strong>Preparing for transplantation early<\/strong> where function is declining. A transplant from a living donor before dialysis begins gives the best outcomes, and relatives being considered as donors need testing for the condition themselves first.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">On the outlook<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The earlier version contained two statements that pulled in opposite directions: that patients <em>cannot avoid<\/em> end-stage kidney failure with age, and that the condition <em>is not serious<\/em> if well understood. Both have been rewritten.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is a serious condition \u2014 and the course varies enormously. Some reach kidney failure in their forties; others have normal function into their seventies and die of something else entirely. Which gene is involved, blood pressure control, and how large the kidneys already are all shape that. <strong>Neither fatalism nor false reassurance is warranted<\/strong>, and what changes the trajectory is regular specialist follow-up rather than waiting for symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions About Polycystic Kidney Disease<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Will my children inherit it?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The common adult form is autosomal dominant, so each child of an affected parent has a one in two chance regardless of sex, and it does not skip generations. Testing relatives is worth discussing deliberately beforehand, since it has implications for insurance and for living-donor assessment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Is there any treatment, or only monitoring?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">There is now a drug, tolvaptan, that slows cyst growth and functional decline in people whose disease is progressing rapidly. It is not a cure and does not suit everyone \u2014 it causes a large increase in thirst and urine output and needs liver monitoring \u2014 but the possibility should be raised with a kidney specialist. An earlier version of this article said no treatment existed beyond blood pressure control.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Should I have my brain scanned?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Not routinely. Screening for brain aneurysms is recommended where there is a family history of aneurysm or of bleeding around the brain, and in some occupations. A sudden severe headache \u2014 the worst of your life \u2014 is an emergency regardless of whether you have been screened.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Will I definitely end up on dialysis?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">No. Around half need dialysis or a transplant by about sixty, which means about half do not, and the course varies widely \u2014 some reach kidney failure in their forties, others retain normal function into their seventies. Blood pressure control and regular follow-up influence which.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Which painkillers can I take for the pain?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Anti-inflammatory painkillers are best avoided where possible because of their effect on kidney function \u2014 an awkward point in a condition whose main symptom is pain, which is why persistent pain should be managed with your specialist rather than with what is available over the counter.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Arranging a consultation<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Polycystic kidney disease is managed jointly with a kidney physician. For its urological complications \u2014 pain, bleeding, infected cysts, stones, and transplant assessment \u2014 Dr. Soarawee Weerasopone sees patients at <a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\">Bangkok Hospital Headquarters<\/a> and at Samitivej Sriracha Hospital in Chonburi on <a href=\"tel:0880221445\">088-022-1445<\/a>. Bring previous scans and kidney function results with their dates, and note any family history of kidney failure, brain aneurysm or stroke at a young age.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bangkok Hospital Telemedicine is available for patients who cannot attend in person, including international patients \u2014 arrange it in advance by email to the Urology department at <a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a>. Samitivej Sriracha is in-person only. Enquiries about cost are answered by the hospital, not by this website.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> This content is written and reviewed by Dr. Soarawee Weerasopone, a board-certified urologist at Bangkok Hospital Headquarters, and is intended for education only. It is not medical advice, diagnosis or a prescription for any individual, and no advice, diagnosis or prescription is given through personal messaging channels or social media. Dr. Soarawee operates no public social media account; any account offering private consultation in his name is fraudulent. In an emergency in Thailand, call <strong>1669<\/strong>.<\/p>\n\n\n\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"MedicalWebPage\",\n      \"@id\": \"https:\/\/drsoaraweeurology.com\/2022\/01\/21\/polycystic-kidney-disease\/#webpage\",\n      \"url\": \"https:\/\/drsoaraweeurology.com\/2022\/01\/21\/polycystic-kidney-disease\/\",\n      \"name\": \"Polycystic Kidney Disease: What It Means, and What Can Now Be Done\",\n      \"description\": \"Autosomal dominant polycystic kidney disease, its renal and extrarenal complications including intracranial aneurysm, and the availability of tolvaptan for rapidly progressive disease.\",\n      \"inLanguage\": \"en\",\n      \"datePublished\": \"2022-01-21\",\n      \"dateModified\": \"2026-08-28\",\n      \"isPartOf\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#website\" },\n      \"author\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"reviewedBy\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"publisher\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"about\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/2022\/01\/21\/polycystic-kidney-disease\/#adpkd\" },\n      \"audience\": { \"@type\": \"MedicalAudience\", \"audienceType\": \"Patient\" },\n      \"disambiguatingDescription\": \"The earlier version stated that no treatment exists beyond blood pressure control and management of complications. 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Testing relatives is worth discussing beforehand given implications for insurance and living-donor assessment.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is there any treatment for polycystic kidney disease?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Tolvaptan slows cyst growth and functional decline in people whose disease is progressing rapidly. It is not a cure, causes a large increase in thirst and urine output and requires liver monitoring, but the possibility should be raised with a kidney specialist.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Should someone with polycystic kidney disease have a brain scan?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Not routinely. Screening for intracranial aneurysm is recommended where there is a family history of aneurysm or subarachnoid haemorrhage and in some occupations. A sudden severe headache is an emergency regardless of screening status.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Does everyone with polycystic kidney disease end up on dialysis?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"No. Around half require dialysis or transplantation by about sixty, meaning about half do not, and the course varies widely. Blood pressure control and regular follow-up influence the trajectory.\" }\n        }\n      ]\n    }\n  ]\n}\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>An inherited condition in which cysts gradually replace both kidneys. Each child of an affected parent has a one in two chance \u2014 and unlike a few years ago, there is now a drug that slows it in those progressing fastest.<\/p>","protected":false},"author":185281453,"featured_media":10079,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"Autosomal dominant polycystic kidney disease: inheritance, the complications urologists treat, the brain aneurysm association, and the drug that now slows progression in selected patients.","jetpack_seo_html_title":"Polycystic Kidney Disease: Management & Warning Signs | Dr. Soarawee","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1364],"tags":[1552,1578],"class_list":["post-4629","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-oncology","tag-oncology-clinic","tag-polycystic-kidney-disease"],"jetpack_publicize_connections":[],"jetpack_likes_enabled":false,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pgZdrK-1cF","jetpack_featured_media_url":"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/04\/Polycystic-Kidney-Disease.webp?fit=1200%2C630&ssl=1","_links":{"self":[{"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/posts\/4629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/users\/185281453"}],"replies":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/comments?post=4629"}],"version-history":[{"count":22,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/posts\/4629\/revisions"}],"predecessor-version":[{"id":11763,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/posts\/4629\/revisions\/11763"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/media\/10079"}],"wp:attachment":[{"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/media?parent=4629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/categories?post=4629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/th\/wp-json\/wp\/v2\/tags?post=4629"}],"curies":[{"name":"\u0e14\u0e31\u0e1a\u0e40\u0e1a\u0e34\u0e25\u0e22\u0e39\u0e1e\u0e35","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}