{"id":10970,"date":"2026-09-02T20:00:00","date_gmt":"2026-09-02T13:00:00","guid":{"rendered":"https:\/\/drsoaraweeurology.com\/?p=10970"},"modified":"2026-09-03T01:58:12","modified_gmt":"2026-09-02T18:58:12","slug":"oral-medications-peyronies-disease","status":"publish","type":"post","link":"https:\/\/drsoaraweeurology.com\/ru\/2026\/09\/02\/oral-medications-peyronies-disease\/","title":{"rendered":"Oral Medications for Peyronie&#8217;s Disease: What Actually Works?"},"content":{"rendered":"\n<div class=\"wp-block-columns coblocks-author-columns has-background is-layout-flex wp-container-core-columns-is-layout-e269d6e6 wp-block-columns-is-layout-flex\" style=\"background-color:#8C8C971A;padding-top:2.5rem;padding-right:2.5rem;padding-bottom:2.5rem;padding-left:2.5rem\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<figure class=\"wp-block-image size-full is-style-rounded\"><img data-recalc-dims=\"1\" fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"800\" data-attachment-id=\"7037\" data-permalink=\"https:\/\/drsoaraweeurology.com\/ru\/new-photo-2024\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" data-orig-size=\"800,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?fit=800%2C800&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=800%2C800&#038;ssl=1\" alt=\"Dr. Soarawee Weerasopone \u2014 Board-Certified Urologist in Bangkok, Thailand\" class=\"wp-image-7037\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?w=800&amp;ssl=1 800w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2023\/12\/New-Photo-2024.png?resize=768%2C768&amp;ssl=1 768w, 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1-.04.342 1.732 1.732 0 0 1-.064.262c-.13.523-.402.913-.815 1.17-.413.255-.95.382-1.61.382z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/orcid.org\/0009-0004-8387-3559\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"ORCID iD\"\n     aria-label=\"View ORCID Profile\"\n     style=\"text-decoration: none; color: #A6CE39; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M12 0C5.372 0 0 5.372 0 12s5.372 12 12 12 12-5.372 12-12S18.628 0 12 0zM7.369 4.378c.525 0 .947.431.947.947 0 .525-.422.947-.947.947-.525 0-.946-.422-.946-.947 0-.525.421-.947.946-.947zm-.722 3.038h1.444v10.041H6.647V7.416zm3.562 0h3.9c3.712 0 5.344 2.653 5.344 5.025 0 2.578-2.016 5.025-5.325 5.025h-3.919V7.416zm1.444 1.303v7.444h2.297c3.272 0 4.022-2.484 4.022-3.722 0-2.016-1.284-3.722-4.097-3.722h-2.222z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/scholar.google.com\/citations?user=lTgsRMUAAAAJ&#038;hl=en\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"Google Scholar\"\n     aria-label=\"View Google Scholar Profile\"\n     style=\"text-decoration: none; color: #4285F4; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M5.242 13.769L0.5 9.5 12 1l11.5 8.5-4.742 4.269C17.548 11.249 14.978 9.5 12 9.5c-2.977 0-5.548 1.748-6.758 4.269zM12 10a7 7 0 1 0 0 14 7 7 0 0 0 0-14z\"\/>\n    <\/svg>\n  <\/a>\n  \n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cDoctor, is there just a pill I can take for this?\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It is almost always the first question a man asks after being told he has <strong>Peyronie&#8217;s disease<\/strong> \u2014 the condition in which a fibrous scar, called a plaque, forms inside the penis and causes it to bend during erection. The hope behind the question is easy to understand. Injections sound uncomfortable. Surgery sounds frightening. A tablet sounds manageable.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">I want to give you the honest answer, because I think men deserve one: <strong>no oral medication has ever been approved anywhere in the world for treating Peyronie&#8217;s disease<\/strong>, and none has been proven to reliably straighten an established curve. That is the headline, and it has not changed despite decades of research.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But that is not the same as saying oral therapy is useless. Some medications still have a legitimate role \u2014 just not the role most men are hoping for. This article walks through what has been tried, what the evidence actually shows, and what a tablet can realistically do for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Before Anything Else: When a Bend Is an Emergency<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Peyronie&#8217;s disease develops gradually, and almost nothing about it is urgent. A few closely related situations are, and they are worth recognising before you read on:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>A sudden bend after an injury during intercourse<\/strong>, particularly with a popping sound or sensation, immediate loss of the erection, pain and rapid bruising or swelling. That is a penile fracture, and it is a surgical emergency \u2014 outcomes are far better when it is repaired early rather than watched.<\/li>\n\n\n\n<li><strong>An erection lasting longer than four hours.<\/strong> Priapism is a urological emergency and needs treatment within hours to protect the tissue permanently. It is relevant here because tadalafil, discussed below, is one of the medications that can rarely trigger it.<\/li>\n\n\n\n<li><strong>Sudden loss of vision or hearing after taking tadalafil or a similar tablet<\/strong> \u2014 rare, but it needs same-day assessment rather than waiting to see whether it settles.<\/li>\n\n\n\n<li><strong>A firm lump in the penis in a man who has never had a bend<\/strong>, especially with skin changes, bleeding or weight loss. That is not typical Peyronie&#8217;s disease and deserves prompt assessment rather than a trial of tablets.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">In Thailand the emergency number is 1669. Everything below assumes none of these applies to you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">First, Timing Matters More Than the Drug<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Peyronie&#8217;s disease moves through two distinct phases, and understanding which phase you are in explains most of what follows.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <strong>acute or active phase<\/strong> typically lasts somewhere between six and eighteen months. During this period, erections are often painful, the curve is still changing, and inflammation is actively driving the scar to form. Think of it as wet cement \u2014 still being poured, still capable of being influenced.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The <strong>chronic or stable phase<\/strong> follows. The pain has usually settled, the curve has stopped changing, and the scar has matured. The cement has set.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Oral medications are considered almost exclusively during the acute phase, and the logic is straightforward: a drug that calms inflammation or interferes with scar formation has a chance of doing something while the scar is still forming. Once the plaque is mature and firm, no tablet is going to dissolve it. That is precisely why treatments delivered directly into the plaque \u2014 and ultimately surgery \u2014 occupy the stable phase instead.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The Medications That Have Been Tried<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Every drug on this list was proposed for a sensible reason. Each targets one of the processes that creates the plaque: inflammation, excess collagen production, oxidative stress, or poor tissue oxygenation. The problem has consistently been that a good idea in the laboratory does not automatically become a good result in patients. Every one of them is used off-label for this condition, meaning the drug was approved for something else entirely.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"800\" data-attachment-id=\"12000\" data-permalink=\"https:\/\/drsoaraweeurology.com\/ru\/2026\/09\/02\/oral-medications-peyronies-disease\/peyronies-oral-medication-tablets\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?fit=800%2C800&amp;ssl=1\" data-orig-size=\"800,800\" data-comments-opened=\"0\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"peyronies-oral-medication-tablets\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?fit=800%2C800&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?resize=800%2C800&#038;ssl=1\" alt=\"Tablets held in an open hand \u2014 every oral drug tried for Peyronie's disease is prescribed off-label, and none is approved for the condition\" class=\"wp-image-12000\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?w=800&amp;ssl=1 800w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?resize=300%2C300&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?resize=150%2C150&amp;ssl=1 150w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?resize=768%2C768&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/peyronies-oral-medication-tablets.jpg?resize=12%2C12&amp;ssl=1 12w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\">Vitamin E \u2014 the most prescribed, and the least justified<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Vitamin E has probably been given to more men with Peyronie&#8217;s disease than any other tablet, mainly because it is cheap, safe, and easy to reach for. The theory was that its antioxidant effect might reduce the tissue damage that leads to scarring.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It does not work. A large, properly designed trial comparing vitamin E against a dummy tablet found no improvement in pain, curvature, or plaque size over six months. The American Urological Association now explicitly recommends against it. It continues to be prescribed anyway \u2014 largely because it feels harmless and patients want to be given <em>something<\/em> \u2014 but men should know they are taking it on hope rather than evidence.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Tamoxifen \u2014 promising in theory, disappointing in practice<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Tamoxifen, a drug better known in breast cancer care, showed genuinely encouraging antifibrotic effects in laboratory studies. When tested in men with Peyronie&#8217;s disease, however, it produced no improvement in pain, curve, or plaque size compared with a dummy tablet. It also carries real side effects, including hot flushes, reduced libido, and a small risk of blood clots. Guidelines recommend against it.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Potaba \u2014 an old option with a heavy burden<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Potassium para-aminobenzoate, sold as Potaba, is one of the oldest treatments for this condition. Trial results were mixed: it did not straighten curves better than a dummy tablet, though plaque size shrank somewhat more.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The practical obstacle is the dose. Treatment requires around twelve grams a day, split across four doses and taken with meals to spare the stomach. That is an enormous number of tablets, often for months, frequently with nausea and diarrhoea. Guidelines disagree about it \u2014 European urologists advise against it, while American and Canadian bodies list it as an option \u2014 which itself tells you how thin the evidence is.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Colchicine \u2014 early promise, later disappointment<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Colchicine, an anti-inflammatory drug long used for gout, interferes with collagen production and encourages the body&#8217;s own collagen-clearing enzymes. Early small studies reported encouraging plaque and curvature improvements, and pain relief was common.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Then a rigorous placebo-controlled trial found no difference from a dummy tablet in pain, curve, or plaque size. Guidelines now file it under \u201cpossibly promising, insufficient evidence.\u201d It is also not a benign drug \u2014 diarrhoea and nausea are common and often dose-limiting, and in men with kidney or liver problems it can cause more serious harm.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pentoxifylline \u2014 interesting, unproven<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Pentoxifylline is a circulation drug with an unusually broad profile: anti-inflammatory, antioxidant, antifibrotic, and vessel-relaxing all at once. Laboratory work on tissue taken from men with Peyronie&#8217;s disease showed it genuinely dampens the collagen-producing signal that drives the plaque \u2014 and did so more strongly in Peyronie&#8217;s tissue than in normal tissue, which is intriguing.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The clinical evidence has not caught up. One study without a proper comparison group reported that most treated men had plaque improvement or stabilisation, considerably more than those left untreated \u2014 but a study with no control group cannot separate the drug from the natural course of the disease, and no rigorous randomised trial has confirmed it. Pentoxifylline sits alongside colchicine in the \u201cpossibly promising\u201d category, and it needs a proper trial rather than more enthusiasm.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The One Genuinely Encouraging Development: Daily Tadalafil<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">If there is a bright spot in oral therapy, this is it.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tadalafil belongs to the same family of medications used for <a href=\"https:\/\/drsoaraweeurology.com\/services\/erectile-dysfunction-bangkok\/\">erectile dysfunction<\/a>. Taken as a small daily dose rather than on demand, it appears to do more than assist erections. By improving blood flow and oxygen delivery to the erectile tissue, it may counteract one of the drivers of scarring \u2014 because poorly oxygenated tissue scars more readily. There is also evidence it interferes directly with the transformation of ordinary cells into the scar-producing cells that build the plaque.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In men studied during the acute phase, a daily low dose of tadalafil slowed the rate at which the curve worsened compared with simply watching and waiting, while also improving erectile function and overall symptoms. A separate study found that internal scars within the penis resolved far more often in treated men than in untreated ones.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Two caveats belong with that, because this is the one place in the article where hope is justified and therefore most easily overstated. The main supporting study was a retrospective comparison rather than a randomised trial, so it can show a difference between groups but not prove the drug caused it. And <strong>tadalafil must never be taken with nitrate medicines for chest pain, or with riociguat<\/strong> \u2014 that combination can cause a sudden and dangerous fall in blood pressure. It also needs care alongside alpha-blockers for prostate symptoms.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Note carefully what is being claimed here. Tadalafil is not straightening existing curves. It appears to <strong>slow the disease down while it is still active<\/strong> \u2014 and because most men with Peyronie&#8217;s disease also have some degree of erectile difficulty, it addresses two problems at once. That combination is why it has become the oral medication I am most willing to discuss with patients in the acute phase.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Newer treatment approaches published in 2026 build daily tadalafil into broader combined protocols \u2014 pairing it with injections into the plaque and daily traction therapy \u2014 reflecting a shift away from searching for one magic tablet and toward attacking the problem from several directions at once.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Oral Therapy Can Realistically Achieve<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Here is how I frame expectations in clinic:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Straightening an established curve \u2014 no.<\/strong> No tablet has demonstrated this reliably in high-quality trials. If a curve is already fixed and troubling you, oral therapy is not the answer.<\/li>\n\n\n\n<li><strong>Slowing progression during the active phase \u2014 possibly.<\/strong> This is where daily tadalafil has shown the most credible promise.<\/li>\n\n\n\n<li><strong>Pain relief \u2014 likely, but be careful how you read it.<\/strong> Pain in Peyronie&#8217;s disease usually resolves on its own within twelve to eighteen months. If pain improves while taking a tablet, the tablet may deserve no credit at all. Simple anti-inflammatory painkillers are a reasonable option for the pain itself.<\/li>\n\n\n\n<li><strong>Shrinking the plaque \u2014 sometimes, but so what?<\/strong> A modest reduction in plaque size that does not change the curve or your ability to have intercourse is a laboratory result, not a clinical one.<\/li>\n\n\n\n<li><strong>As part of a wider plan \u2014 yes.<\/strong> Oral medication works best as one component alongside traction, injections, and careful monitoring \u2014 not as a substitute for them.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">The most thorough independent review of non-surgical treatments for this condition reached a blunt conclusion: there is little good evidence that they work, and most trials have been too small or too poorly designed to answer the question properly. That is an uncomfortable finding, but pretending otherwise does patients no favours.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The only medication formally approved for Peyronie&#8217;s disease anywhere is not a tablet at all \u2014 it is an injection placed directly into the plaque. I have written separately about <a href=\"https:\/\/drsoaraweeurology.com\/2026\/08\/26\/xiaflex-peyronies-disease-non-surgical-treatment\/\">how that injection treatment works and who qualifies for it<\/a>. It is not in routine use here; if it is something you are interested in, please email the Urology department at <a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a> to enquire first.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Side Effects Worth Knowing About<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Because these medications are used off-label with modest expected benefit, their side effects carry proportionally more weight in the decision.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Potaba:<\/strong> nausea, loss of appetite, diarrhoea, and a punishing number of tablets each day. Must be taken with food.<\/li>\n\n\n\n<li><strong>Vitamin E:<\/strong> usually well tolerated, but sustained high doses have been linked in some analyses to increased cardiovascular risk. Not as harmless as it looks.<\/li>\n\n\n\n<li><strong>Colchicine:<\/strong> diarrhoea and nausea are common. In men with kidney or liver impairment, more serious effects on blood counts, muscles, and nerves can occur, and it interacts with a number of other medications.<\/li>\n\n\n\n<li><strong>Tamoxifen:<\/strong> hot flushes, stomach upset, reduced libido, and a small risk of blood clots.<\/li>\n\n\n\n<li><strong>Pentoxifylline:<\/strong> nausea, dizziness, headache. Not suitable after recent bleeding in the brain or eye, and requires caution alongside blood thinners.<\/li>\n\n\n\n<li><strong>Tadalafil:<\/strong> headache, facial flushing, blocked nose, indigestion, back or muscle ache. <strong>It must never be combined with nitrate heart medications or riociguat<\/strong>, needs care alongside alpha-blockers and in men with significant heart disease, and rarely can cause a prolonged erection or sudden visual or hearing loss \u2014 all of which need urgent attention.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Always tell your urologist about every medication and supplement you take. Several of these interact in ways that matter. And do not start, stop or change any of them on your own \u2014 that includes stopping a medicine you suspect is contributing.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"12001\" data-permalink=\"https:\/\/drsoaraweeurology.com\/ru\/2026\/09\/02\/oral-medications-peyronies-disease\/pharmacy-medication-counter\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"0\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;,&quot;alt&quot;:&quot;&quot;}\" data-image-title=\"pharmacy-medication-counter\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Medicines being dispensed at a pharmacy counter \u2014 several of these drugs interact with others, so nothing should be started or stopped without the prescribing doctor\" class=\"wp-image-12001\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/09\/pharmacy-medication-counter.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/figure>\n\n<h2 class=\"wp-block-heading\">The Bottom Line<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Decades of research into oral medication for Peyronie&#8217;s disease have produced a long list of sensible ideas and very few convincing results. Vitamin E and tamoxifen are recommended against. Potaba, colchicine, and pentoxifylline remain unproven, and each brings side effects that are difficult to justify for an uncertain benefit. Daily low-dose tadalafil is the one agent with genuinely encouraging recent evidence \u2014 and even then, its role is to slow the disease during the active phase and improve erections, not to straighten a curve that has already set.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you take one message from this article, let it be this: <strong>do not spend the active phase of your disease waiting for a tablet to fix it.<\/strong> That window is when the condition is most influenceable, and it is far better spent under proper assessment \u2014 establishing which phase you are in, measuring the curve accurately, checking your erectile function, and building a plan that may combine medication, traction, injections, and if necessary surgery.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">See how <a href=\"https:\/\/drsoaraweeurology.com\/services\/peyronies-disease-treatment\/\">Peyronie&#8217;s disease treatment<\/a> is structured in practice, including when <a href=\"https:\/\/drsoaraweeurology.com\/services\/penile-prosthesis-bangkok\/\">penile prosthesis surgery<\/a> becomes the more appropriate route.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you have noticed a bend developing, pain with erections, or difficulty with intercourse, please seek assessment rather than self-medicating. Dr. Soarawee Weerasopone offers specialist consultations in men&#8217;s health and Peyronie&#8217;s disease at <a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" target=\"_blank\" rel=\"noreferrer noopener\">Bangkok Hospital Headquarters<\/a> and at <a href=\"tel:0880221445\">Samitivej Sriracha Hospital, Chonburi \u2014 088-022-1445<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bangkok Hospital Telemedicine is available for patients who cannot attend in person, including international patients \u2014 arrange it in advance by email to the Urology department at <a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a>. Samitivej Sriracha is in-person only. For any enquiry about the cost of consultation or treatment, please contact the hospital directly at the same address, or Samitivej Sriracha on <a href=\"tel:0880221445\">088-022-1445<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions About Oral Medications for Peyronie&#8217;s Disease<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Is there a pill that cures Peyronie&#8217;s disease?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">No. No oral medication has been approved anywhere in the world for Peyronie&#8217;s disease, and none has been shown in high-quality trials to reliably straighten an established curve. Every oral agent used for this condition is prescribed off-label. The only formally approved medication is an injection placed directly into the plaque, not a tablet. Oral therapy is best understood as a way to possibly slow the disease during its active phase and manage symptoms, rather than as a cure.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Does vitamin E help Peyronie&#8217;s disease?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">The evidence says no. A large, well-designed trial comparing vitamin E against a dummy tablet found no improvement in pain, curvature, or plaque size over six months, and the American Urological Association explicitly recommends against its use. It is still widely prescribed because it is cheap and feels harmless, but sustained high doses have been linked in some analyses to increased cardiovascular risk, so it is not entirely without downside.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can daily tadalafil help Peyronie&#8217;s disease?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Daily low-dose tadalafil is the most encouraging oral option currently available. In men studied during the acute phase, it slowed the rate at which the curve worsened compared with observation alone, while also improving erectile function. It appears to work by improving blood flow and oxygen delivery to the erectile tissue, since poorly oxygenated tissue scars more readily. Two honest caveats: the main supporting study was a retrospective comparison rather than a randomised trial, and tadalafil must never be combined with nitrate heart medicines or riociguat. Importantly, it is not straightening existing curves \u2014 its value lies in slowing active disease and treating the erectile difficulty that commonly accompanies Peyronie&#8217;s disease.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">When should oral medication be started for Peyronie&#8217;s disease?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Oral medication is considered almost exclusively during the acute or active phase, which typically lasts six to eighteen months and is marked by painful erections and a curve that is still changing. During this window the scar is still forming and may be influenceable. Once the disease enters the stable phase, with pain resolved and the curve fixed, no tablet will dissolve a mature plaque, and treatments delivered directly into the plaque or surgery become the appropriate options.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">When is a penile bend an emergency?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">A sudden bend following an injury during intercourse \u2014 particularly with a popping sound or sensation, immediate loss of the erection, pain and rapid swelling or bruising \u2014 suggests a penile fracture, which is a surgical emergency and does far better when repaired early. An erection lasting more than four hours is also an emergency. So is sudden loss of vision or hearing after taking tadalafil or a similar tablet. A new firm lump in a man who has never had a bend, especially with skin changes or weight loss, needs prompt assessment rather than a trial of tablets. In Thailand the emergency number is 1669.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Can I discuss Peyronie&#8217;s disease by telemedicine before travelling to Bangkok?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Yes, for the initial conversation. Bangkok Hospital Telemedicine is available for patients who cannot attend in person, including international patients, and is arranged in advance by email to the Urology department at bhquro@bdms.co.th. It is a sensible first step for reviewing your history and current medications. A curve cannot be measured remotely, however, so the deformity must be assessed in person before a treatment plan is settled. Samitivej Sriracha is in-person only.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">References<\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Nehra A, Alterowitz R, Culkin DJ, et al. Peyronie&#8217;s disease: AUA guideline. <em>J Urol.<\/em> 2015;194(3):745\u2013753. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26066402\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Chierigo F, Fallara G, Tozzi M, et al. Guideline of guidelines: Peyronie&#8217;s disease. <em>BJU Int.<\/em> 2026;137(5):770\u2013782. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41795618\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Rosenberg JE, Ergun O, Hwang EC, et al. Non-surgical therapies for Peyronie&#8217;s disease. <em>Cochrane Database Syst Rev.<\/em> 2023;7:CD012206. <a href=\"https:\/\/www.cochranelibrary.com\/cdsr\/doi\/10.1002\/14651858.CD012206.pub2\/full\" target=\"_blank\" rel=\"noreferrer noopener\">Cochrane Library<\/a><\/li>\n\n\n\n<li>Spirito L, Manfredi C, La Rocca R, et al. Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie&#8217;s disease: a retrospective comparative analysis. <em>Int J Impot Res.<\/em> 2024;36(2):129\u2013134. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36513814\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Safarinejad MR, Hosseini SY, Kolahi AA. Comparison of vitamin E and propionyl-L-carnitine, separately or in combination, in patients with early chronic Peyronie&#8217;s disease. <em>J Urol.<\/em> 2007;178(4):1398\u20131403. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17706714\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Safarinejad MR. Therapeutic effects of colchicine in the management of Peyronie&#8217;s disease: a randomized double-blind, placebo-controlled study. <em>Int J Impot Res.<\/em> 2004;16(3):238\u2013243. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/14985780\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Ilg MM, Mateus M, Stebbeds WJ, et al. Antifibrotic synergy between phosphodiesterase type 5 inhibitors and selective oestrogen receptor modulators in Peyronie&#8217;s disease models. <em>Eur Urol.<\/em> 2019;75(2):329\u2013340. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30344087\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n\n\n\n<li>Hayat S, Brunckhorst O, Alnajjar HM, et al. A systematic review of non-surgical management in Peyronie&#8217;s disease. <em>Int J Impot Res.<\/em> 2023;35(6):523\u2013532. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36289392\" target=\"_blank\" rel=\"noreferrer noopener\">PubMed<\/a><\/li>\n<\/ol>\n\n\n\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"MedicalWebPage\",\n      \"@id\": \"https:\/\/drsoaraweeurology.com\/2026\/09\/02\/oral-medications-peyronies-disease\/#webpage\",\n      \"url\": \"https:\/\/drsoaraweeurology.com\/2026\/09\/02\/oral-medications-peyronies-disease\/\",\n      \"name\": \"Oral Medications for Peyronie's Disease: What Actually Works?\",\n      \"headline\": \"Oral Medications for Peyronie's Disease: What Actually Works?\",\n      \"description\": \"An evidence-based review of oral medications for Peyronie's disease \u2014 vitamin E, tamoxifen, Potaba, colchicine, pentoxifylline and daily low-dose tadalafil \u2014 what tablets can realistically achieve during the active and stable phases, and which related situations are emergencies.\",\n      \"inLanguage\": \"en\",\n      \"datePublished\": \"2026-09-02\",\n      \"dateModified\": \"2026-08-18\",\n      \"lastReviewed\": \"2026-08-18\",\n      \"isPartOf\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#website\" },\n      \"author\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"reviewedBy\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"publisher\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/#physician\" },\n      \"specialty\": \"https:\/\/schema.org\/Urologic\",\n      \"audience\": {\n        \"@type\": \"MedicalAudience\",\n        \"audienceType\": \"Patient\"\n      },\n      \"disambiguatingDescription\": \"No oral medication is approved anywhere for Peyronie's disease; every agent discussed is used off-label. Collagenase injection is not in routine use at this clinic and enquiries should go by email to the Urology department.\",\n      \"about\": {\n        \"@type\": \"MedicalCondition\",\n        \"name\": \"Peyronie's disease\",\n        \"associatedAnatomy\": { \"@type\": \"AnatomicalStructure\", \"name\": \"Tunica albuginea of the penis\" },\n        \"signOrSymptom\": [\n          { \"@type\": \"MedicalSignOrSymptom\", \"name\": \"Penile curvature during erection\" },\n          { \"@type\": \"MedicalSignOrSymptom\", \"name\": \"Painful erections during the active phase\" },\n          { \"@type\": \"MedicalSignOrSymptom\", \"name\": \"Palpable penile plaque\" }\n        ],\n        \"possibleTreatment\": [\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Daily low-dose tadalafil (off-label)\",\n            \"description\": \"The most encouraging oral option. Appears to slow curvature progression during the acute phase and improve erectile function; it does not straighten an established curve. Main supporting evidence is a retrospective comparative analysis rather than a randomised trial.\",\n            \"contraindication\": {\n              \"@type\": \"MedicalContraindication\",\n              \"name\": \"Concurrent nitrate or riociguat therapy\",\n              \"description\": \"Absolute contraindication because of the risk of severe hypotension. Caution alongside alpha-blockers and in significant cardiac disease.\"\n            },\n            \"seriousAdverseOutcome\": [\n              { \"@type\": \"MedicalEntity\", \"name\": \"Priapism \u2014 an erection lasting longer than four hours requires emergency treatment\" },\n              { \"@type\": \"MedicalEntity\", \"name\": \"Sudden loss of vision or hearing requiring same-day assessment\" }\n            ]\n          },\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Vitamin E (off-label)\",\n            \"description\": \"Recommended against by the American Urological Association. A placebo-controlled trial found no improvement in pain, curvature or plaque size.\"\n          },\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Tamoxifen (off-label)\",\n            \"description\": \"Recommended against. No improvement over placebo in pain, curvature or plaque size, with meaningful side effects.\"\n          },\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Potassium para-aminobenzoate (Potaba, off-label)\",\n            \"description\": \"Did not straighten curves better than placebo. Guidelines disagree; the dose burden is roughly twelve grams daily in four divided doses.\"\n          },\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Colchicine (off-label)\",\n            \"description\": \"A placebo-controlled trial found no difference in pain, curvature or plaque size. Dose-limiting gastrointestinal effects; more serious harm possible in renal or hepatic impairment.\"\n          },\n          {\n            \"@type\": \"MedicalTherapy\",\n            \"name\": \"Pentoxifylline (off-label)\",\n            \"description\": \"Laboratory evidence of antifibrotic effect; clinical evidence limited to an uncontrolled study that cannot separate the drug from the natural course of the disease.\"\n          }\n        ]\n      },\n      \"mentions\": [\n        {\n          \"@type\": \"MedicalCondition\",\n          \"name\": \"Penile fracture\",\n          \"description\": \"A sudden bend after injury during intercourse, with a popping sensation, immediate loss of erection, pain and rapid swelling, is a surgical emergency with better outcomes after early repair.\"\n        },\n        {\n          \"@type\": \"MedicalCondition\",\n          \"name\": \"Priapism\",\n          \"description\": \"An erection lasting longer than four hours is a urological emergency requiring treatment within hours.\"\n        }\n      ]\n    },\n    {\n      \"@type\": \"FAQPage\",\n      \"@id\": \"https:\/\/drsoaraweeurology.com\/2026\/09\/02\/oral-medications-peyronies-disease\/#faq\",\n      \"isPartOf\": { \"@id\": \"https:\/\/drsoaraweeurology.com\/2026\/09\/02\/oral-medications-peyronies-disease\/#webpage\" },\n      \"mainEntity\": [\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Is there a pill that cures Peyronie's disease?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"No. No oral medication has been approved anywhere in the world for Peyronie's disease, and none has been shown in high-quality trials to reliably straighten an established curve. Every oral agent used for this condition is prescribed off-label. The only formally approved medication is an injection placed directly into the plaque, not a tablet. Oral therapy is best understood as a way to possibly slow the disease during its active phase and manage symptoms, rather than as a cure.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Does vitamin E help Peyronie's disease?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"The evidence says no. A large, well-designed trial comparing vitamin E against a dummy tablet found no improvement in pain, curvature or plaque size over six months, and the American Urological Association explicitly recommends against its use. It is still widely prescribed because it is cheap and feels harmless, but sustained high doses have been linked in some analyses to increased cardiovascular risk, so it is not entirely without downside.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can daily tadalafil help Peyronie's disease?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Daily low-dose tadalafil is the most encouraging oral option currently available. In men studied during the acute phase it slowed the rate at which the curve worsened compared with observation alone, while also improving erectile function. Two honest caveats: the main supporting study was a retrospective comparison rather than a randomised trial, and tadalafil must never be combined with nitrate heart medicines or riociguat. It is not straightening existing curves; its value lies in slowing active disease and treating the erectile difficulty that commonly accompanies Peyronie's disease.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"When should oral medication be started for Peyronie's disease?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Oral medication is considered almost exclusively during the acute or active phase, which typically lasts six to eighteen months and is marked by painful erections and a curve that is still changing. During this window the scar is still forming and may be influenceable. Once the disease enters the stable phase, with pain resolved and the curve fixed, no tablet will dissolve a mature plaque, and treatments delivered directly into the plaque or surgery become the appropriate options.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"When is a penile bend an emergency?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"A sudden bend following an injury during intercourse, particularly with a popping sound or sensation, immediate loss of the erection, pain and rapid swelling or bruising, suggests a penile fracture, which is a surgical emergency and does far better when repaired early. An erection lasting more than four hours is also an emergency, as is sudden loss of vision or hearing after taking tadalafil or a similar tablet. A new firm lump in a man who has never had a bend, especially with skin changes or weight loss, needs prompt assessment rather than a trial of tablets. In Thailand the emergency number is 1669.\" }\n        },\n        {\n          \"@type\": \"Question\",\n          \"name\": \"Can I discuss Peyronie's disease by telemedicine before travelling to Bangkok?\",\n          \"acceptedAnswer\": { \"@type\": \"Answer\", \"text\": \"Yes, for the initial conversation. Bangkok Hospital Telemedicine is available for patients who cannot attend in person, including international patients, and is arranged in advance by email to the Urology department at bhquro@bdms.co.th. It is a sensible first step for reviewing your history and current medications. A curve cannot be measured remotely, however, so the deformity must be assessed in person before a treatment plan is settled. Samitivej Sriracha is in-person only.\" }\n        }\n      ]\n    }\n  ]\n}\n<\/script>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> This content is written and reviewed by Dr. Soarawee Weerasopone, a board-certified urologist at Bangkok Hospital Headquarters. It is intended for educational purposes only and does not constitute medical advice. Every oral medication discussed here is used off-label for Peyronie&#8217;s disease, and none is approved for it. Dr. Soarawee does not provide medical assessment, advice, diagnosis or prescriptions through personal messaging channels, direct messages or social media. Always consult a qualified healthcare professional before starting, stopping or changing any medical treatment. In an emergency, attend the nearest emergency department \u2014 in Thailand the emergency number is 1669.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Is there a pill I can just take for this?&#8221; It is the first question almost every man with Peyronie&#8217;s disease asks. Dr. Soarawee Weerasopone gives an honest answer \u2014 which oral medications are worth considering, which are not, and what oral therapy can realistically achieve.<\/p>","protected":false},"author":185281453,"featured_media":11581,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"No oral medication is approved for Peyronie's disease, but some are still worth considering. Dr. Soarawee, urologist at Bangkok Hospital, explains vitamin E, colchicine, pentoxifylline, Potaba, and daily tadalafil \u2014 what the evidence really shows.","jetpack_seo_html_title":"Oral Medications for Peyronie's Disease: What Works? | Dr. Pom Bangkok","jetpack_seo_noindex":false,"jetpack_seo_schema_type":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"{title}\n\n{excerpt}\n\n{url}","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"_wpas_customize_per_network":false,"jetpack_post_was_ever_published":false},"categories":[1363],"tags":[],"class_list":["post-10970","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mens-health"],"jetpack_publicize_connections":[],"jetpack_likes_enabled":false,"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pgZdrK-2QW","jetpack_featured_media_url":"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2026\/08\/peyronies-oral-medication-featured.jpg?fit=1200%2C630&ssl=1","_links":{"self":[{"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/posts\/10970","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/users\/185281453"}],"replies":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/comments?post=10970"}],"version-history":[{"count":11,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/posts\/10970\/revisions"}],"predecessor-version":[{"id":12003,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/posts\/10970\/revisions\/12003"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/media\/11581"}],"wp:attachment":[{"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/media?parent=10970"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/categories?post=10970"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drsoaraweeurology.com\/ru\/wp-json\/wp\/v2\/tags?post=10970"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}