{"id":4548,"date":"2021-12-31T08:00:00","date_gmt":"2021-12-31T01:00:00","guid":{"rendered":"https:\/\/drsoaraweeurology.com\/?p=4548"},"modified":"2026-05-18T09:49:31","modified_gmt":"2026-05-18T02:49:31","slug":"therapie-de-privation-androgenique","status":"publish","type":"post","link":"https:\/\/drsoaraweeurology.com\/fr\/2021\/12\/31\/androgen-deprivation-therapy\/","title":{"rendered":"Th\u00e9rapie de privation androg\u00e9nique chez un patient atteint d'un cancer de la prostate avanc\u00e9"},"content":{"rendered":"\n<div class=\"wp-block-columns coblocks-author-columns has-background is-layout-flex wp-container-core-columns-is-layout-52275889 wp-block-columns-is-layout-flex\" style=\"background-color:#8C8C971A;padding-top:2.5rem;padding-right:2.5rem;padding-bottom:2.5rem;padding-left:2.5rem\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:25%\">\n<figure class=\"wp-block-image size-full is-style-rounded\"><img 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1.255.564 2.073.564.8 0 1.536-.213 2.105-.603.57-.39.94-.916 1.175-1.65.076-.235.135-.558.177-.93a15.4 15.4 0 0 0 .063-1.207v-.512a.27.27 0 0 0-.273-.273h-2.95a.27.27 0 0 0-.274.273v.785c0 .228.0.343.273.343h1.337c.094 0 .14.045.14.137 0 .61-.063 1.043-.155 1.318-.182.546-.7 1.018-1.683 1.018-.654 0-1.135-.114-1.475-.356-.34-.244-.55-.585-.658-1.024a3.797 3.797 0 0 1-.111-.43 5.515 5.515 0 0 1-.06-.51 19.85 19.85 0 0 1-.025-.726c-.004-.28-.004-.628-.004-1.045 0-.418 0-.766.004-1.046a19.85 19.85 0 0 1 .025-.726 5.475 5.475 0 0 1 .06-.51 3.785 3.785 0 0 1 .111-.43c.108-.44.318-.78.658-1.024.34-.243.82-.357 1.475-.357.6 0 1.064.078 1.413.293.347.215.595.515.74.91.063.155.166.21.31.156l.967-.4c.15-.058.187-.18.13-.32a3.025 3.025 0 0 0-1.262-1.452C21.12.218 20.428.0 19.586 0zM8.512 4.32c-2.7 0-4.066.997-4.066 3.06v.04c0 1.92.992 2.83 3.046 2.83 1.27 0 2.038-.39 2.385-1.05h.13l.067.51c.04.2.207.34.41.34h.99V7.95c0-2.59-1.06-3.63-2.962-3.63zm-.18 1.61c1.118 0 1.628.56 1.628 1.86v.4l-1.65.16c-1.35.13-1.86.46-1.86 1.13v.04c0 .67.41 1.06 1.45 1.06.85 0 1.55-.32 1.93-.84.04-.06.13-.07.18-.02.05.03.07.1.07.16v.43c0 .26.13.42.34.42h1.05c.21 0 .34-.16.34-.42v-3.6c0-1.94-1.13-2.83-3.46-2.83-1.94 0-3.07.86-3.4 2.04l1.55.45c.18-.69.6-1.04 1.83-1.04zM2.135 16.314c-.587 0-1.066-.156-1.434-.469-.367-.312-.618-.704-.752-1.176-.034-.124-.061-.232-.082-.327a3.794 3.794 0 0 1-.044-.366 8.83 8.83 0 0 1-.022-.547C0 13.221 0 12.985 0 12.704c0-.281 0-.515.001-.704a8.81 8.81 0 0 1 .022-.547 3.802 3.802 0 0 1 .044-.366c.02-.094.048-.203.082-.328.134-.471.385-.864.752-1.176.368-.313.847-.469 1.434-.469.477 0 .892.087 1.246.262.353.175.622.443.806.804.044.083.083.157.117.222.034.066.069.144.105.235.022.054.011.099-.034.135l-.66.292c-.045.027-.082.013-.112-.045a4.043 4.043 0 0 0-.155-.27 1.247 1.247 0 0 0-.49-.495c-.225-.131-.522-.196-.892-.196-.402 0-.726.064-.972.193-.247.13-.422.302-.527.518-.027.045-.054.099-.082.16a1.39 1.39 0 0 0-.067.197 2.46 2.46 0 0 0-.05.282 5.51 5.51 0 0 0-.033.43c-.008.17-.013.376-.013.617 0 .242.005.448.013.618.008.17.02.314.034.43.013.117.03.21.05.282.02.072.042.137.066.197.105.216.28.39.527.518.246.13.57.193.972.193.4 0 .714-.07.94-.21.227-.14.394-.346.503-.617a2.43 2.43 0 0 0 .104-.395c.018-.123.027-.282.027-.477V13.2H2.34c-.04 0-.06-.02-.06-.062v-.5c0-.04.02-.062.06-.062h1.812c.04 0 .062.02.062.06v.5c0 .156-.005.296-.014.422a4.71 4.71 0 0 1-.04.342 1.732 1.732 0 0 1-.064.262c-.13.523-.402.913-.815 1.17-.413.255-.95.382-1.61.382z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/orcid.org\/0009-0004-8387-3559\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"ORCID iD\"\n     aria-label=\"View ORCID Profile\"\n     style=\"text-decoration: none; color: #A6CE39; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M12 0C5.372 0 0 5.372 0 12s5.372 12 12 12 12-5.372 12-12S18.628 0 12 0zM7.369 4.378c.525 0 .947.431.947.947 0 .525-.422.947-.947.947-.525 0-.946-.422-.946-.947 0-.525.421-.947.946-.947zm-.722 3.038h1.444v10.041H6.647V7.416zm3.562 0h3.9c3.712 0 5.344 2.653 5.344 5.025 0 2.578-2.016 5.025-5.325 5.025h-3.919V7.416zm1.444 1.303v7.444h2.297c3.272 0 4.022-2.484 4.022-3.722 0-2.016-1.284-3.722-4.097-3.722h-2.222z\"\/>\n    <\/svg>\n  <\/a>\n  \n  <a href=\"https:\/\/scholar.google.com\/citations?user=lTgsRMUAAAAJ&#038;hl=en\" \n     target=\"_blank\" \n     rel=\"noopener\"\n     title=\"Google Scholar\"\n     aria-label=\"View Google Scholar Profile\"\n     style=\"text-decoration: none; color: #4285F4; transition: transform 0.2s; display: inline-block;\"\n     onmouseover=\"this.style.transform='scale(1.15)'\"\n     onmouseout=\"this.style.transform='scale(1)'\">\n    <svg width=\"28\" height=\"28\" viewBox=\"0 0 24 24\" fill=\"currentColor\">\n      <path d=\"M5.242 13.769L0.5 9.5 12 1l11.5 8.5-4.742 4.269C17.548 11.249 14.978 9.5 12 9.5c-2.977 0-5.548 1.748-6.758 4.269zM12 10a7 7 0 1 0 0 14 7 7 0 0 0 0-14z\"\/>\n    <\/svg>\n  <\/a>\n  \n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">In this topic, we will remain focusing on androgen deprivation therapy (ADT) in advanced prostate cancer patients. Testosterone plays a major role in prostate cancer aggressiveness; therefore, we try in every way to suppress this hormone to control disease progression.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Urology center Bangkok hospital Thailand\u00a0<a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\" target=\"_blank\" rel=\"noreferrer noopener\">Booking online<\/a>\u00a0<a href=\"tel:02-310-3009\">02-310-3009<\/a>\u00a0<a href=\"mailto:bhquro@bdms.co.th\">bhquro@bdms.co.th<\/a><\/li>\n\n\n\n<li>Samitivej Sriracha hospital Chonburi&nbsp;<a href=\"tel:088-022-1445\">088-022-1445<\/a><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4566\" data-permalink=\"https:\/\/drsoaraweeurology.com\/fr\/2021\/12\/31\/androgen-deprivation-therapy\/portrait-of-an-old-elderly-asian-man-holds-the-head-with-his-hand-cause-of-stress-after-try-to-use-a-computer-laptop-in-the-backyard-after-retired-concept-of-ageism-and-hobbies-after-retirement\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.2&quot;,&quot;credit&quot;:&quot;Prot Tachapanit&quot;,&quot;camera&quot;:&quot;ILCE-6500&quot;,&quot;caption&quot;:&quot;Portrait of an old elderly Asian man holds the head with his hand cause of stress after try to use a computer laptop in the backyard after retired. Concept of Ageism and Hobbies after retirement.&quot;,&quot;created_timestamp&quot;:&quot;1601867531&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;35&quot;,&quot;iso&quot;:&quot;100&quot;,&quot;shutter_speed&quot;:&quot;0.00625&quot;,&quot;title&quot;:&quot;Portrait of an old elderly Asian man holds the head with his hand cause of stress after try to use a computer laptop in the backyard after retired. Concept of Ageism and Hobbies after retirement.&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Both local and foreigner are seeking for a good quality service with an up-to-date management in prostate cancer treatment in Cambodia.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Both local and foreigner are seeking for a good quality service with an up-to-date management in prostate cancer treatment in Cambodia.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Androgen deprivation therapy in advanced prostate cancer\" class=\"wp-image-4566\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Upset-old-man.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Patients are seeking for good quality, up-to-date management in prostate cancer treatment.<\/figcaption><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" decoding=\"async\" width=\"800\" height=\"479\" data-attachment-id=\"4567\" data-permalink=\"https:\/\/drsoaraweeurology.com\/fr\/2021\/12\/31\/androgen-deprivation-therapy\/male-health-concept-tiny-characters-patients-and-doctor-at-huge-testosterone-formula-man-hold-mars-sign-hormones-2\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?fit=1200%2C719&amp;ssl=1\" data-orig-size=\"1200,719\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;Male Health Concept. Tiny Characters Patients and Doctor at Huge Testosterone Formula. Man Hold Mars Sign. Hormones, Diagnostics and Treatment Poster Banner Flyer. Cartoon People Vector Illustration&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;Male Health Concept. Tiny Characters Patients and Doctor at Huge Testosterone Formula. Man Hold Mars Sign. Hormones&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"Testosterone plays a major role in prostate cancer aggressiveness activity.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;Testosterone plays a major role in prostate cancer aggressiveness activity.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?fit=800%2C480&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?resize=800%2C479&#038;ssl=1\" alt=\"Testosterone and prostate cancer\" class=\"wp-image-4567\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?resize=300%2C180&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?resize=1024%2C614&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?resize=768%2C460&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Testosterone.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Testosterone plays a major role in prostate cancer aggressiveness activity.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">In the past, the only way to perform androgen deprivation therapy was a bilateral orchiectomy (surgical testicular removal), which dramatically suppressed testosterone by removing the primary production organ. However, confirmed reports showed that patients who underwent orchiectomy sometimes confronted psychological trauma from this irreversible procedure.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Currently, modern medical ADT has been developed. These preparations come as subcutaneous or intramuscular injections with intervals ranging from 1 month to 1 year. Regular serum testosterone measurement is still required to confirm adequate suppression.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4564\" data-permalink=\"https:\/\/drsoaraweeurology.com\/fr\/2021\/12\/31\/androgen-deprivation-therapy\/doctors-in-sugery-room-sending-medical-device-to-other-in-operation\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;4&quot;,&quot;credit&quot;:&quot;Sura Nualpradid&quot;,&quot;camera&quot;:&quot;Canon EOS 5D Mark IV&quot;,&quot;caption&quot;:&quot;Doctors in sugery room sending medical device to other in operation.&quot;,&quot;created_timestamp&quot;:&quot;1518358528&quot;,&quot;copyright&quot;:&quot;Sura Nualpradid&quot;,&quot;focal_length&quot;:&quot;150&quot;,&quot;iso&quot;:&quot;200&quot;,&quot;shutter_speed&quot;:&quot;0.005&quot;,&quot;title&quot;:&quot;Doctors in sugery room sending medical device to other in operation&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"In the past, in order to control the testosterone hormone, there was only one way; a testicular-removal-surgery.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;In the past, in order to control the testosterone hormone, there was only one way; a testicular-removal-surgery.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Androgen deprivation therapy history\" class=\"wp-image-4564\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Surgical-ADT.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">In the past, testicular removal surgery was the only option to suppress testosterone.<\/figcaption><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">Examples of <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19440008\/\">Medical Androgen Deprivation Therapy<\/a><\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Enantone (Leuprolide)\n\n<ul class=\"wp-block-list\">\n<li>95%\u201398.8% complete testosterone suppression reported (cut-off: &lt;50 ng\/dL)<\/li>\n<\/ul>\n<\/li>\n\n\n<li>Zoladex (Goserelin)\n\n<ul class=\"wp-block-list\">\n<li>96% complete testosterone suppression reported (cut-off: &lt;20 ng\/dL)<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\">My current practice is 3-month interval intramuscular injection with regular monitoring including:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>PSA (Prostate Specific Antigen) \u2014 using PSA Doubling Time to assess cancer activity<\/li>\n\n\n<li>Testosterone level \u2014 target &lt;50 ng\/dL per NCCN 2021 guideline<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"533\" data-attachment-id=\"4563\" data-permalink=\"https:\/\/drsoaraweeurology.com\/fr\/2021\/12\/31\/androgen-deprivation-therapy\/doctor-man-consulting-patient-while-filling-up-an-application-form-at-the-desk-in-hospital-medicine-and-health-care-concept\/\" data-orig-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?fit=1200%2C800&amp;ssl=1\" data-orig-size=\"1200,800\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;2.8&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;Canon EOS 5D Mark III&quot;,&quot;caption&quot;:&quot;Doctor man consulting patient while filling up an application form at the desk in hospital. Medicine and health care concept&quot;,&quot;created_timestamp&quot;:&quot;1560786346&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;100&quot;,&quot;iso&quot;:&quot;125&quot;,&quot;shutter_speed&quot;:&quot;0.033333333333333&quot;,&quot;title&quot;:&quot;Doctor man consulting patient while filling up an application form at the desk in hospital. Medicine and health care concept&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"It is a duty of Uro-Oncologist to stay tune up-to-date in advance prostate cancer management.\" data-image-description=\"\" data-image-caption=\"&lt;p&gt;It is a duty of Uro-Oncologist to stay tune up-to-date in advance prostate cancer management.&lt;\/p&gt;\n\" data-large-file=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?fit=800%2C534&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?resize=800%2C533&#038;ssl=1\" alt=\"Uro-oncologist prostate cancer management\" class=\"wp-image-4563\" srcset=\"https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?w=1200&amp;ssl=1 1200w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?resize=300%2C200&amp;ssl=1 300w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?resize=1024%2C683&amp;ssl=1 1024w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?resize=768%2C512&amp;ssl=1 768w, https:\/\/i0.wp.com\/drsoaraweeurology.com\/wp-content\/uploads\/2021\/12\/Good-doctor.jpg?resize=18%2C12&amp;ssl=1 18w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">It is a duty of a Uro-Oncologist to stay up-to-date in advanced prostate cancer management.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">The current practice in prostate cancer management keeps updating every 3 months. This is just one small aspect of prostate cancer care \u2014 discussing your treatment with an up-to-date Uro-Oncologist is essential for a tailor-made androgen deprivation therapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">You can visit my official website <a href=\"https:\/\/drsoaraweeurology.com\/\">here<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions About Androgen Deprivation Therapy (ADT)<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">What is androgen deprivation therapy and why is it used in prostate cancer?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Androgen deprivation therapy (ADT) is the primary systemic treatment for advanced prostate cancer. Testosterone fuels prostate cancer cell growth and aggressiveness, so ADT works by suppressing testosterone to castrate levels (&lt;50 ng\/dL). This can be achieved surgically through bilateral orchiectomy or medically through regular injections of LHRH agonists such as Leuprolide (Enantone) or Goserelin (Zoladex).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What is the difference between surgical and medical ADT?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Surgical ADT (orchiectomy) is a one-time irreversible procedure that permanently removes the testosterone-producing testicular tissue. It is highly effective but can cause significant psychological impact. Medical ADT uses injectable LHRH agonists at intervals of 1 month to 1 year, achieving 95\u201398.8% testosterone suppression. Medical ADT requires ongoing injections and regular testosterone monitoring to confirm adequate suppression, but preserves the option to discontinue treatment.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">How is ADT treatment response monitored?<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Treatment response is monitored every 3 months through PSA measurement \u2014 specifically PSA Doubling Time to track cancer activity \u2014 and serum testosterone levels targeting below 50 ng\/dL per NCCN guidelines. Rising PSA on ADT may indicate disease progression and the need to consider additional second-line treatments. Regular follow-up with a Uro-Oncologist is essential for timely treatment adjustment.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">If you or a family member has been diagnosed with advanced prostate cancer and requires ADT consultation, Dr. Soarawee Weerasopone offers specialist consultations at Bangkok Hospital Headquarters. <a href=\"https:\/\/www.bangkokhospital.com\/en\/bangkok\/doctor\/dr-soarawee-weerasopone-2\">Book a Consultation<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Disclaimer:<\/strong> This content is written and reviewed by Dr. Soarawee Weerasopone, a board-certified urologist at Bangkok Hospital Headquarters. It is intended for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any medical treatment.<\/p>\n\n\n\n<script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@type\": \"FAQPage\",\n  \"mainEntity\": [\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is androgen deprivation therapy and why is it used in prostate cancer?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"ADT suppresses testosterone to castrate levels (<50 ng\/dL) to control prostate cancer growth. It can be surgical (orchiectomy) or medical using LHRH agonist injections such as Leuprolide (Enantone) or Goserelin (Zoladex).\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"What is the difference between surgical and medical ADT?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"Surgical ADT (orchiectomy) is a one-time irreversible procedure with permanent testosterone suppression but potential psychological impact. Medical ADT uses LHRH agonist injections at 1-month to 1-year intervals, achieving 95-98.8% testosterone suppression with ongoing monitoring and the option to discontinue.\"\n      }\n    },\n    {\n      \"@type\": \"Question\",\n      \"name\": \"How is ADT treatment response monitored?\",\n      \"acceptedAnswer\": {\n        \"@type\": \"Answer\",\n        \"text\": \"ADT is monitored every 3 months with PSA (PSA Doubling Time) and serum testosterone targeting <50 ng\/dL per NCCN guidelines. Rising PSA on ADT may indicate progression requiring second-line treatment adjustment.\"\n      }\n    }\n  ]\n}\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>In this topic, we will remain focusing on androgen deprivation therapy (ADT) in advanced prostate cancer patients. Testosterone plays a major role in prostate cancer aggressiveness; therefore, we try in every way to suppress this hormone to control disease progression. In the past, the only way to perform androgen deprivation therapy was a bilateral orchiectomy [&hellip;]<\/p>\n","protected":false},"author":185281453,"featured_media":10017,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"Learn about androgen deprivation therapy (ADT) for advanced prostate cancer \u2014 surgical vs medical options, monitoring, and treatment goals. 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